| 148* | MA Carberry | Hampshire v Scotland | The Ageas Bowl, Southampton | a21992 |
| 143 | P Mustard | Durham v Surrey | Emirates Durham International Cricket Ground, Chester-le-Street | a22075 |
| 143 | SW Billings | Kent v Derbyshire | St Lawrence Ground, Canterbury | a22077 |
| 137 | JJ Cobb | Leicestershire v Lancashire | Old Trafford, Manchester | a21953 |
| 137* | CB Cooke | Glamorgan v Somerset | County Ground, Taunton | a22059 |
| 136* | MD Stoneman | Durham v Scotland | Emirates Durham International Cricket Ground, Chester-le-Street | a21978 |
| 134 | DJ Malan | Middlesex v Essex | Lord's Cricket Ground, St John's Wood | a22106 |
| 133 | RJ Nicol | Gloucestershire v Netherlands | VRA Ground, Amstelveen | a22057 |
| 126* | MW Machan | Sussex v Unicorns | The PROBIZ County Ground, Hove | a21967 |
| 125 | MJ Guptill | Derbyshire v Unicorns | Sir Paul Getty's Ground, Wormsley | a21955 |
| 122* | CJL Rogers | Middlesex v Gloucestershire | College Ground, Cheltenham | a22049 |
| 122 | LJ Wright | Sussex v Hampshire | The PROBIZ County Ground, Hove | a22116 |
| 121 | VS Solanki | Worcestershire v Lancashire | Old Trafford, Manchester | a21995 |
| 120* | WJ Durston | Derbyshire v Unicorns | Sir Paul Getty's Ground, Wormsley | a21955 |
| 120* | RS Bopara | Essex v Gloucestershire | The Ford County Ground, Chelmsford | a21991 |
| 120* | EJG Morgan | Middlesex v Worcestershire | Uxbridge Cricket Club Ground, Uxbridge | a22070 |
| 119 | PR Stirling | Middlesex v Lancashire | Lord's Cricket Ground, St John's Wood | a22003 |
| 116 | EJG Morgan | Middlesex v Lancashire | Lord's Cricket Ground, St John's Wood | a22003 |
| 115* | JWA Taylor | Nottinghamshire v Hampshire | The Ageas Bowl, Southampton | a21985 |
| 115 | RR Sarwan | Leicestershire v Netherlands | Grace Road, Leicester | a21993 |
| 113 | SC Moore | Lancashire v Worcestershire | County Ground, New Road, Worcester | a22109 |
| 112 | KS Williamson | Gloucestershire v Leicestershire | County Ground, Bristol | a21965 |
| 112* | MD Stoneman | Durham v Glamorgan | Emirates Durham International Cricket Ground, Chester-le-Street | a22076 |
| 111 | PJ Hughes | Worcestershire v Middlesex | County Ground, New Road, Worcester | a21981 |
| 111 | ML Pettini | Essex v Worcestershire | County Ground, New Road, Worcester | a22062 |
| 110 | J Symes | Scotland v Durham | Emirates Durham International Cricket Ground, Chester-le-Street | a21978 |
| 110 | V Chopra | Warwickshire v Lancashire | Old Trafford, Manchester | a22115 |
| 107 | P Mustard | Durham v Glamorgan | Emirates Durham International Cricket Ground, Chester-le-Street | a22076 |
| 106 | TC Smith | Lancashire v Worcestershire | County Ground, New Road, Worcester | a22109 |
| 105 | MA Wallace | Glamorgan v Durham | Emirates Durham International Cricket Ground, Chester-le-Street | a22076 |
| 104 | PJ Hughes | Worcestershire v Lancashire | Old Trafford, Manchester | a21995 |
| 104 | Usman Khawaja | Derbyshire v Unicorns | Queen's Park, Chesterfield | a22033 |
| 103 | LJ Wright | Sussex v Yorkshire | The PROBIZ County Ground, Hove | a21977 |
| 103* | MA Carberry | Hampshire v Somerset | County Ground, Taunton | a21980 |
| 103* | GS Ballance | Yorkshire v Unicorns | North Marine Road, Scarborough | a21982 |
| 103 | C Kieswetter | Somerset v Durham | County Ground, Taunton | a22052 |
| 102 | EC Joyce | Sussex v Unicorns | The PROBIZ County Ground, Hove | a21967 |
| 102 | MR Swart | Netherlands v Leicestershire | Grace Road, Leicester | a21993 |
| 102* | JM Vince | Hampshire v Nottinghamshire | Trent Bridge, Nottingham | a22041 |
| 102 | MD Stoneman | Durham v Nottinghamshire | Trent Bridge, Nottingham | a22089 |
| 101 | RJ Hamilton-Brown | Surrey v Somerset | The Kia Oval, Kennington | a21951 |
| 101 | RWT Key | Kent v Yorkshire | St Lawrence Ground, Canterbury | a22097 |
| 101* | LJ Wright | Sussex v Kent | St Lawrence Ground, Canterbury | a22104 |
| 100 | P Mustard | Durham v Nottinghamshire | Emirates Durham International Cricket Ground, Chester-le-Street | a21988 |
| 100 | RR Sarwan | Leicestershire v Worcestershire | Grace Road, Leicester | a22030 |
| 100* | WTS Porterfield | Warwickshire v Unicorns | Sir Paul Getty's Ground, Wormsley | a22091 |
