| Runs |
Out of |
4s |
6s |
| 140 | 162* | 11 | 16 | | Hazratullah Zazai | Afghanistan v Ireland | Rajiv Gandhi International Cricket Stadium, Dehra Dun | 2018/19 |
| 88 | 118* | 10 | 8 | | Mohammad Shahzad | Afghanistan v Zimbabwe | Sharjah Cricket Association Stadium, Sharjah | 2015/16 |
| 78 | 89 | 6 | 9 | | Mohammad Nabi | Afghanistan v Ireland | Greater Noida Sports Complex Ground, Greater Noida | 2016/17 |
| 68 | 74 | 8 | 6 | | Hazratullah Zazai | Afghanistan v Ireland | Magheramason, Bready | 2018 |
| 70 | 100 | 7 | 7 | | Rahmanullah Gurbaz | Afghanistan v United Arab Emirates | Sharjah Cricket Association Stadium, Sharjah | 2023/24 |
| 66 | 82 | 6 | 7 | | Hazratullah Zazai | Afghanistan v Ireland | Magheramason, Bready | 2018 |
| 66 | 81 | 6 | 7 | | Mohammad Nabi | Afghanistan v Ireland | Rajiv Gandhi International Cricket Stadium, Dehra Dun | 2018/19 |
| 66 | 87 | 6 | 7 | | Rahmanullah Gurbaz | Afghanistan v Zimbabwe | Sheikh Zayed Stadium, Abu Dhabi | 2020/21 |
| 58 | 74 | 7 | 5 | | Mohammad Shahzad | Afghanistan v United Arab Emirates | Raeburn Place, Edinburgh | 2015 |
| 62 | 75 | 5 | 7 | | Mohammad Shahzad | Afghanistan v Scotland | Raeburn Place, Edinburgh | 2015 |
| 58 | 90 | 7 | 5 | | Najeeb Tarakai | Afghanistan v Ireland | Greater Noida Sports Complex Ground, Greater Noida | 2016/17 |
| 50 | 80 | 8 | 3 | | Mohammad Shahzad | Afghanistan v Oman | Dubai Sports City Stadium, Dubai | 2016/17 |
| 54 | 72 | 6 | 5 | | Mohammad Shahzad | Afghanistan v Ireland | Greater Noida Sports Complex Ground, Greater Noida | 2016/17 |
| 56 | 69* | 5 | 6 | | Najibullah Zadaran | Afghanistan v Zimbabwe | Shere Bangla National Stadium, Mirpur | 2019/20 |
| 54 | 79 | 6 | 5 | | Rahmanullah Gurbaz | Afghanistan v West Indies | Bharat Ratna Shri Atal Bihari Vajpayee Ekana Cricket Stadium, Lucknow | 2019/20 |
| 42 | 69 | 9 | 1 | | Usman Ghani | Afghanistan v Oman | Sheikh Zayed Stadium, Abu Dhabi | 2015/16 |
| 42 | 52* | 9 | 1 | | Mohammad Shahzad | Afghanistan v Ireland | Dubai Sports City Stadium, Dubai | 2016/17 |
| 46 | 73 | 7 | 3 | | Usman Ghani | Afghanistan v Ireland | Rajiv Gandhi International Cricket Stadium, Dehra Dun | 2018/19 |
| 54 | 84* | 3 | 7 | | Mohammad Nabi | Afghanistan v Bangladesh | Shere Bangla National Stadium, Mirpur | 2019/20 |
| 50 | 72* | 5 | 5 | | Najibullah Zadaran | Afghanistan v Zimbabwe | Sheikh Zayed Stadium, Abu Dhabi | 2020/21 |
| 52 | 84 | 4 | 6 | | Rahmanullah Gurbaz | Afghanistan v Sri Lanka | Sharjah Cricket Association Stadium, Sharjah | 2022 |
| 42 | 61 | 6 | 3 | | Samiullah Shenwari | Afghanistan v Canada | ICC Cricket Academy Ground, Dubai | 2011/12 |
| 40 | 77 | 7 | 2 | | Mohammad Shahzad | Afghanistan v Ireland | Dubai Sports City Stadium, Dubai | 2011/12 |
| 38 | 38 | 8 | 1 | | Mohammad Shahzad | Afghanistan v Ireland | Sheikh Zayed Stadium, Abu Dhabi | 2013/14 |
| 42 | 68 | 6 | 3 | | Mohammad Shahzad | Afghanistan v Hong Kong | Zohur Ahmed Chowdhury Stadium, Chittagong | 2013/14 |
| 42 | 65 | 6 | 3 | | Usman Ghani | Afghanistan v Zimbabwe | Queens Sports Club, Bulawayo | 2015/16 |
| 38 | 72 | 8 | 1 | | Karim Sadiq | Afghanistan v United Arab Emirates | Khan Shaheb Osman Ali Stadium, Fatullah | 2015/16 |
| 42 | 56 | 6 | 3 | | Samiullah Shenwari | Afghanistan v Ireland | Greater Noida Sports Complex Ground, Greater Noida | 2016/17 |
| 42 | 73 | 6 | 3 | | Najibullah Zadaran | Afghanistan v New Zealand | Sheikh Zayed Stadium, Abu Dhabi | 2021/22 |
| 38 | 53 | 8 | 1 | | Rahmanullah Gurbaz | Afghanistan v Ireland | Civil Service Cricket Club, Stormont, Belfast | 2022 |
| 46 | 56* | 4 | 5 | | Karim Janat | Afghanistan v United Arab Emirates | Sheikh Zayed Stadium, Abu Dhabi | 2022/23 |
| 44 | 57 | 5 | 4 | | Gulbadeen Naib | Afghanistan v India | Holkar Stadium, Indore | 2023/24 |
| 42 | 59 | 6 | 3 | | Mohammad Nabi | Afghanistan v Ireland | Sharjah Cricket Association Stadium, Sharjah | 2023/24 |
