| 1-68 | KJ Abbott | South Africa v West Indies | Bidvest Wanderers Stadium, Johannesburg | 2014/15 |
| 0-67 | SSB Magala | South Africa v West Indies | SuperSport Park, Centurion | 2022/23 |
| 1-63 | AL Phehlukwayo | South Africa v England | Seat Unique Stadium, Bristol | 2022 |
| 0-58 | D Wiese | South Africa v Australia | Bidvest Wanderers Stadium, Johannesburg | 2015/16 |
| 0-57 | T Shamsi | South Africa v England | PPC Newlands, Cape Town | 2020/21 |
| 0-57 | K Rabada | South Africa v India | Nehru Stadium, Guwahati | 2022/23 |
| 0-56 | BE Hendricks | South Africa v England | PPC Newlands, Cape Town | 2020/21 |
| 0-55 | BE Hendricks | South Africa v Pakistan | SuperSport Park, Centurion | 2020/21 |
| 2-55 | LT Ngidi | South Africa v England | SuperSport Park, Centurion | 2019/20 |
| 0-54 | WD Parnell | South Africa v India | Nehru Stadium, Guwahati | 2022/23 |
| 1-52 | SM Pollock | South Africa v West Indies | Liberty Life Wanderers Stadium, Johannesburg | 2007/08 |
| 3-52 | M Jansen | South Africa v West Indies | SuperSport Park, Centurion | 2022/23 |
| 0-51 | D Paterson | South Africa v India | SuperSport Park, Centurion | 2017/18 |
| 2-51 | LT Ngidi | South Africa v England | Eurolux Boland Park, Paarl | 2020/21 |
| 2-51 | LT Ngidi | South Africa v India | Holkar Stadium, Indore | 2022/23 |
| 0-50 | DW Steyn | South Africa v England | Kensington Oval, Bridgetown | 2010 |
| 0-50 | M Morkel | South Africa v New Zealand | Zohur Ahmed Chowdhury Stadium, Chittagong | 2013/14 |
| 1-50 | BE Hendricks | South Africa v England | Zohur Ahmed Chowdhury Stadium, Chittagong | 2013/14 |
| 2-50 | K Rabada | South Africa v England | Wankhede Stadium, Mumbai | 2015/16 |
| 2-50 | K Rabada | South Africa v West Indies | Imperial Wanderers Stadium, Johannesburg | 2022/23 |
| 0-49 | LL Tsotsobe | South Africa v Sri Lanka | Mahinda Rajapaksha International Cricket Stadium, Hambantota | 2013 |
| 0-49 | T Shamsi | South Africa v England | Seat Unique Stadium, Bristol | 2022 |
| 0-49 | LT Ngidi | South Africa v India | Nehru Stadium, Guwahati | 2022/23 |
| 0-49 | LT Ngidi | South Africa v Australia | Hollywoodbets Kingsmead, Durban | 2023/24 |
| 1-49 | LT Ngidi | South Africa v West Indies | Queen's Park (New), St George's | 2021 |
| 0-48 | D Paterson | South Africa v India | Bidvest Wanderers Stadium, Johannesburg | 2017/18 |
| 0-48 | LT Ngidi | South Africa v West Indies | Queen's Park (New), St George's | 2021 |
| 2-48 | RK Kleinveldt | South Africa v India | Beausejour Stadium, Gros Islet | 2010 |
| 3-48 | LT Ngidi | South Africa v England | Hollywoodbets Kingsmead, Durban | 2019/20 |
| 3-48 | K Rabada | South Africa v England | Sharjah Cricket Association Stadium, Sharjah | 2021/22 |
