| Runs |
Out of |
4s |
6s |
| 82 | 101 | 16 | 3 | | L Lee | South Africa Women v Thailand Women | Manuka Oval, Canberra | 2019/20 |
| 58 | 90* | 13 | 1 | | D van Niekerk | South Africa Women v Pakistan Women | Sylhet Stadium, Sylhet | 2013/14 |
| 38 | 67* | 8 | 1 | | L Lee | South Africa Women v Pakistan Women | Sylhet Stadium, Sylhet | 2013/14 |
| 32 | 53* | 8 | 0 | | L Wolvaardt | South Africa Women v Pakistan Women | Sydney Showground Stadium, Sydney | 2019/20 |
| 34 | 66* | 7 | 1 | | L Wolvaardt | South Africa Women v Bangladesh Women | PPC Newlands, Cape Town | 2022/23 |
| 36 | 68 | 6 | 2 | | T Brits | South Africa Women v England Women | PPC Newlands, Cape Town | 2022/23 |
| 38 | 61 | 5 | 3 | | L Wolvaardt | South Africa Women v Australia Women | PPC Newlands, Cape Town | 2022/23 |
| 30 | 39 | 6 | 1 | | SA Fritz | South Africa Women v Australia Women | County Ground, Taunton | 2009 |
| 32 | 61* | 5 | 2 | | SE Luus | South Africa Women v Thailand Women | Manuka Oval, Canberra | 2019/20 |
| 30 | 45 | 6 | 1 | | T Brits | South Africa Women v Australia Women | St George's Park, Gqeberha | 2022/23 |
| 24 | 38 | 6 | 0 | | M du Preez | South Africa Women v West Indies Women | County Ground, Taunton | 2009 |
| 24 | 36 | 6 | 0 | | T Chetty | South Africa Women v Australia Women | County Ground, Taunton | 2009 |
| 28 | 53* | 4 | 2 | | M du Preez | South Africa Women v Australia Women | Warner Park, Basseterre | 2010 |
| 26 | 43 | 5 | 1 | | L Lee | South Africa Women v Ireland Women | Sylhet Stadium, Sylhet | 2013/14 |
| 24 | 29 | 6 | 0 | | SE Luus | South Africa Women v Ireland Women | Sylhet Stadium, Sylhet | 2013/14 |
| 30 | 35* | 3 | 3 | | CL Tryon | South Africa Women v Ireland Women | Sylhet Stadium, Sylhet | 2013/14 |
| 24 | 38 | 6 | 0 | | M Kapp | South Africa Women v England Women | Western Australia Cricket Association Ground, Perth | 2019/20 |
| 24 | 40 | 6 | 0 | | CL Tryon | South Africa Women v New Zealand Women | Eurolux Boland Park, Paarl | 2022/23 |
| 26 | 53 | 5 | 1 | | L Wolvaardt | South Africa Women v England Women | PPC Newlands, Cape Town | 2022/23 |
| 20 | 44 | 5 | 0 | | SM Benade | South Africa Women v New Zealand Women | County Ground, Taunton | 2009 |
| 20 | 57* | 5 | 0 | | C Brits | South Africa Women v New Zealand Women | County Ground, Taunton | 2009 |
| 20 | 51 | 5 | 0 | | M du Preez | South Africa Women v New Zealand Women | Sylhet Stadium, Sylhet | 2013/14 |
| 24 | 40 | 3 | 2 | | CL Tryon | South Africa Women v England Women | Shere Bangla National Stadium, Mirpur | 2013/14 |
| 22 | 45 | 4 | 1 | | D van Niekerk | South Africa Women v Australia Women | Vidarbha Cricket Association Stadium, Nagpur | 2015/16 |
| 22 | 38 | 4 | 1 | | M Kapp | South Africa Women v Sri Lanka Women | Daren Sammy National Cricket Stadium, Gros Islet | 2018/19 |
| 24 | 41* | 3 | 2 | | L Wolvaardt | South Africa Women v Australia Women | Sydney Cricket Ground, Sydney | 2019/20 |
| 20 | 43 | 2 | 2 | | C Brits | South Africa Women v West Indies Women | Warner Park, Basseterre | 2010 |
| 18 | 58 | 3 | 1 | | SA Fritz | South Africa Women v West Indies Women | Warner Park, Basseterre | 2010 |
| 20 | 24 | 2 | 2 | | SM Benade | South Africa Women v New Zealand Women | Galle International Stadium, Galle | 2012/13 |
| 16 | 31 | 4 | 0 | | AL Hodgkinson | South Africa Women v New Zealand Women | Galle International Stadium, Galle | 2012/13 |
| 16 | 34* | 4 | 0 | | D van Niekerk | South Africa Women v New Zealand Women | Galle International Stadium, Galle | 2012/13 |
| 16 | 30 | 4 | 0 | | T Chetty | South Africa Women v Australia Women | Sylhet Stadium, Sylhet | 2013/14 |
| 18 | 19* | 3 | 1 | | SE Luus | South Africa Women v Australia Women | Sylhet Stadium, Sylhet | 2013/14 |
| 16 | 35 | 4 | 0 | | T Chetty | South Africa Women v Ireland Women | MA Chidambaram Stadium, Chepauk, Chennai | 2015/16 |
| 16 | 24 | 4 | 0 | | D Devnarain | South Africa Women v Ireland Women | MA Chidambaram Stadium, Chepauk, Chennai | 2015/16 |
| 18 | 30* | 3 | 1 | | L Lee | South Africa Women v Ireland Women | MA Chidambaram Stadium, Chepauk, Chennai | 2015/16 |
| 20 | 46 | 2 | 2 | | D van Niekerk | South Africa Women v England Women | Western Australia Cricket Association Ground, Perth | 2019/20 |
| 16 | 22 | 4 | 0 | | SE Luus | South Africa Women v New Zealand Women | Eurolux Boland Park, Paarl | 2022/23 |
| 16 | 50* | 4 | 0 | | T Brits | South Africa Women v Bangladesh Women | PPC Newlands, Cape Town | 2022/23 |
| 16 | 27* | 4 | 0 | | M Kapp | South Africa Women v England Women | PPC Newlands, Cape Town | 2022/23 |
