| Runs |
Out of |
4s |
6s |
| 100 | 145 | 13 | 8 | | Rahmanullah Gurbaz | Afghanistan v Bangladesh | Zohur Ahmed Chowdhury Stadium, Chittagong | 2023 |
| 84 | 162 | 15 | 4 | | Ibrahim Zadran | Afghanistan v Sri Lanka | Pallekele Cricket Stadium, Pallekele | 2022/23 |
| 88 | 149* | 13 | 6 | | Azmatullah Omarzai | Afghanistan v Sri Lanka | Pallekele Cricket Stadium, Pallekele | 2023/24 |
| 86 | 124 | 11 | 7 | | Mohammad Shahzad | Afghanistan v India | Dubai Sports City Stadium, Dubai | 2018 |
| 78 | 136 | 15 | 3 | | Mohammad Nabi | Afghanistan v Sri Lanka | Pallekele Cricket Stadium, Pallekele | 2023/24 |
| 84 | 177 | 12 | 6 | | Ibrahim Zadran | Afghanistan v England | Gaddafi Stadium, Lahore | 2024/25 |
| 86 | 127 | 8 | 9 | | Rahmanullah Gurbaz | Afghanistan v Ireland | Sheikh Zayed Stadium, Abu Dhabi | 2020/21 |
| 74 | 151 | 14 | 3 | | Rahmanullah Gurbaz | Afghanistan v Pakistan | Mahinda Rajapaksha International Cricket Stadium, Hambantota | 2023 |
| 72 | 100 | 12 | 4 | | Karim Sadiq | Afghanistan v Netherlands | Sharjah Cricket Association Stadium, Sharjah | 2011/12 |
| 64 | 101 | 16 | 0 | | Mohammad Shahzad | Afghanistan v Ireland | Civil Service Cricket Club, Stormont, Belfast | 2019 |
| 64 | 120* | 16 | 0 | | Ibrahim Zadran | Afghanistan v Zimbabwe | Harare Sports Club, Harare | 2022 |
| 60 | 100* | 15 | 0 | | Mohammad Shahzad | Afghanistan v Scotland | Cambusdoon New Ground, Alloway | 2010 |
| 76 | 131* | 7 | 8 | | Mohammad Shahzad | Afghanistan v Zimbabwe | Sharjah Cricket Association Stadium, Sharjah | 2015/16 |
| 62 | 114* | 11 | 3 | | Karim Sadiq | Afghanistan v Scotland | Cambusdoon New Ground, Alloway | 2010 |
| 68 | 112* | 8 | 6 | | Nawroz Mangal | Afghanistan v Scotland | Sharjah Cricket Association Stadium, Sharjah | 2012/13 |
| 66 | 89* | 9 | 5 | | Najibullah Zadaran | Afghanistan v Scotland | Raeburn Place, Edinburgh | 2016 |
| 68 | 121 | 8 | 6 | | Rahmanullah Gurbaz | Afghanistan v Ireland | Sharjah Cricket Association Stadium, Sharjah | 2023/24 |
| 56 | 118 | 11 | 2 | | Mohammad Shahzad | Afghanistan v Canada | Sharjah Cricket Association Stadium, Sharjah | 2009/10 |
| 56 | 95 | 11 | 2 | | Shabir Noori | Afghanistan v Canada | Maple Leaf North-West Ground, King City | 2011 |
| 54 | 118 | 12 | 1 | | Usman Ghani | Afghanistan v Zimbabwe | Queens Sports Club, Bulawayo | 2014 |
| 64 | 83 | 7 | 6 | | Najibullah Zadaran | Afghanistan v Ireland | Dubai Sports City Stadium, Dubai | 2014/15 |
| 58 | 75* | 10 | 3 | | Mohammad Shahzad | Afghanistan v Zimbabwe | Sharjah Cricket Association Stadium, Sharjah | 2017/18 |
| 56 | 84 | 11 | 2 | | Mohammad Shahzad | Afghanistan v West Indies | Harare Sports Club, Harare | 2017/18 |
| 56 | 113 | 11 | 2 | | Rahmat Shah | Afghanistan v Scotland | Raeburn Place, Edinburgh | 2019 |
| 52 | 88 | 13 | 0 | | Hashmatullah Shahidi | Afghanistan v Zimbabwe | Harare Sports Club, Harare | 2022 |
| 56 | 98 | 11 | 2 | | Ibrahim Zadran | Afghanistan v Sri Lanka | Mahinda Rajapaksha International Cricket Stadium, Hambantota | 2023 |
| 58 | 105 | 10 | 3 | | Rahmanullah Gurbaz | Afghanistan v South Africa | Sharjah Cricket Association Stadium, Sharjah | 2024/25 |
| 52 | 114 | 10 | 2 | | Noor Ali Zadran | Afghanistan v Canada | Sharjah Cricket Association Stadium, Sharjah | 2009/10 |
| 56 | 129 | 8 | 4 | | Nawroz Mangal | Afghanistan v United Arab Emirates | ICC Cricket Academy Ground, Dubai | 2014/15 |
| 50 | 67 | 11 | 1 | | Javed Ahmadi | Afghanistan v United Arab Emirates | ICC Cricket Academy Ground, Dubai | 2014/15 |
| 58 | 96 | 7 | 5 | | Samiullah Shenwari | Afghanistan v Scotland | University Oval, Dunedin | 2014/15 |
| 60 | 101 | 6 | 6 | | Asghar Stanikzai | Afghanistan v Ireland | Greater Noida Sports Complex Ground, Greater Noida | 2016/17 |
| 48 | 63 | 12 | 0 | | Mohammad Shahzad | Afghanistan v Ireland | Greater Noida Sports Complex Ground, Greater Noida | 2016/17 |
| 56 | 114 | 8 | 4 | | Rahmat Shah | Afghanistan v Zimbabwe | Sharjah Cricket Association Stadium, Sharjah | 2017/18 |
| 52 | 103* | 10 | 2 | | Rahmat Shah | Afghanistan v Ireland | Sheikh Zayed Stadium, Abu Dhabi | 2020/21 |
| 56 | 80 | 8 | 4 | | Rahmanullah Gurbaz | Afghanistan v England | Feroz Shah Kotla, Delhi | 2023/24 |
| 62 | 101 | 5 | 7 | | Rahmanullah Gurbaz | Afghanistan v Bangladesh | Sharjah Cricket Association Stadium, Sharjah | 2024/25 |
| 50 | 84 | 11 | 1 | | Abdul Malik | Afghanistan v Zimbabwe | Harare Sports Club, Harare | 2024/25 |
| 56 | 104 | 8 | 4 | | Sediqullah Atal | Afghanistan v Zimbabwe | Harare Sports Club, Harare | 2024/25 |
