| 270 | Nazmul Hossain | Bangladesh v Afghanistan | Shere Bangla National Stadium, Mirpur | 2023 |
| 189 | SC Williams | Zimbabwe v Afghanistan | Queens Sports Club, Bulawayo | 2024/25 |
| 159 | SC Williams | Zimbabwe v Afghanistan | Sheikh Zayed Stadium, Abu Dhabi | 2020/21 |
| 141 | AD Mathews | Sri Lanka v Afghanistan | Sinhalese Sports Club Ground, Colombo | 2023/24 |
| 136 | Mominul Haque | Bangladesh v Afghanistan | Shere Bangla National Stadium, Mirpur | 2023 |
| 128 | CR Ervine | Zimbabwe v Afghanistan | Queens Sports Club, Bulawayo | 2024/25 |
| 126 | CR Ervine | Zimbabwe v Afghanistan | Queens Sports Club, Bulawayo | 2024/25 |
| 111 | SSJ Brooks | West Indies v Afghanistan | Bharat Ratna Shri Atal Bihari Vajpayee Ekana Cricket Stadium, Lucknow | 2019/20 |
| 110 | BJ Bennett | Zimbabwe v Afghanistan | Queens Sports Club, Bulawayo | 2024/25 |
| 109 | FDM Karunaratne | Sri Lanka v Afghanistan | Sinhalese Sports Club Ground, Colombo | 2023/24 |
| 109 | BJ Curran | Zimbabwe v Afghanistan | Queens Sports Club, Bulawayo | 2024/25 |
| 107 | S Dhawan | India v Afghanistan | M Chinnaswamy Stadium, Bangalore | 2018 |
| 107 | Sikandar Raza | Zimbabwe v Afghanistan | Sheikh Zayed Stadium, Abu Dhabi | 2020/21 |
| 107 | LD Chandimal | Sri Lanka v Afghanistan | Sinhalese Sports Club Ground, Colombo | 2023/24 |
| 105 | M Vijay | India v Afghanistan | M Chinnaswamy Stadium, Bangalore | 2018 |
| 105 | SC Williams | Zimbabwe v Afghanistan | Sheikh Zayed Stadium, Abu Dhabi | 2020/21 |
| 99 | Sikandar Raza | Zimbabwe v Afghanistan | Queens Sports Club, Bulawayo | 2024/25 |
| 98 | DT Tiripano | Zimbabwe v Afghanistan | Sheikh Zayed Stadium, Abu Dhabi | 2020/21 |
| 93 | Mahmudul Hasan | Bangladesh v Afghanistan | Shere Bangla National Stadium, Mirpur | 2023 |
| 86 | A Balbirnie | Ireland v Afghanistan | Rajiv Gandhi International Cricket Stadium, Dehra Dun | 2018/19 |
| 81 | TJ Murtagh | Ireland v Afghanistan | Rajiv Gandhi International Cricket Stadium, Dehra Dun | 2018/19 |
| 80 | PS Masvaure | Zimbabwe v Afghanistan | Sheikh Zayed Stadium, Abu Dhabi | 2020/21 |
| 75 | Liton Das | Bangladesh v Afghanistan | Shere Bangla National Stadium, Mirpur | 2023 |
| 74 | JD Campbell | West Indies v Afghanistan | Bharat Ratna Shri Atal Bihari Vajpayee Ekana Cricket Stadium, Lucknow | 2019/20 |
| 73 | LJ Tucker | Ireland v Afghanistan | Tolerance Oval, Abu Dhabi | 2023/24 |
| 72 | Zakir Hasan | Bangladesh v Afghanistan | Shere Bangla National Stadium, Mirpur | 2023 |
| 71 | HH Pandya | India v Afghanistan | M Chinnaswamy Stadium, Bangalore | 2018 |
| 71 | KT Kasuza | Zimbabwe v Afghanistan | Sheikh Zayed Stadium, Abu Dhabi | 2020/21 |
| 68 | KJ O'Brien | Ireland v Afghanistan | Rajiv Gandhi International Cricket Stadium, Dehra Dun | 2018/19 |
| 66 | PR Stirling | Ireland v Afghanistan | Tolerance Oval, Abu Dhabi | 2023/24 |
