| 2-154 | Rashid Khan | Afghanistan v India | M Chinnaswamy Stadium, Bangalore | 2018 |
| 4-138 | Rashid Khan | Afghanistan v Zimbabwe | Sheikh Zayed Stadium, Abu Dhabi | 2020/21 |
| 7-137 | Rashid Khan | Afghanistan v Zimbabwe | Sheikh Zayed Stadium, Abu Dhabi | 2020/21 |
| 2-127 | Zahir Khan | Afghanistan v Zimbabwe | Queens Sports Club, Bulawayo | 2024/25 |
| 3-127 | Allah Ghazanfar | Afghanistan v Zimbabwe | Queens Sports Club, Bulawayo | 2024/25 |
| 3-114 | Rashid Khan | Afghanistan v West Indies | Bharat Ratna Shri Atal Bihari Vajpayee Ekana Cricket Stadium, Lucknow | 2019/20 |
| 2-112 | Zahir Khan | Afghanistan v Bangladesh | Shere Bangla National Stadium, Mirpur | 2023 |
| 2-109 | Naveed Zadran | Afghanistan v Zimbabwe | Queens Sports Club, Bulawayo | 2024/25 |
| 1-104 | Hamza Hotak | Afghanistan v Zimbabwe | Sheikh Zayed Stadium, Abu Dhabi | 2020/21 |
| 2-101 | Zia-ur-Rehman | Afghanistan v Zimbabwe | Queens Sports Club, Bulawayo | 2024/25 |
| 2-100 | Wafadar Momand | Afghanistan v India | M Chinnaswamy Stadium, Bangalore | 2018 |
| 1-98 | Zahir Khan | Afghanistan v Bangladesh | Shere Bangla National Stadium, Mirpur | 2023 |
| 2-98 | Qais Ahmad | Afghanistan v Sri Lanka | Sinhalese Sports Club Ground, Colombo | 2023/24 |
| 4-94 | Rashid Khan | Afghanistan v Zimbabwe | Queens Sports Club, Bulawayo | 2024/25 |
| 0-90 | Zia-ur-Rehman | Afghanistan v Sri Lanka | Sinhalese Sports Club Ground, Colombo | 2023/24 |
| 1-90 | Hamza Hotak | Afghanistan v Bangladesh | Shere Bangla National Stadium, Mirpur | 2023 |
| 1-85 | Hamza Hotak | Afghanistan v Bangladesh | Shere Bangla National Stadium, Mirpur | 2023 |
| 0-83 | Nijat Masood | Afghanistan v Bangladesh | Shere Bangla National Stadium, Mirpur | 2023 |
| 4-83 | Naveed Zadran | Afghanistan v Sri Lanka | Sinhalese Sports Club Ground, Colombo | 2023/24 |
| 5-82 | Rashid Khan | Afghanistan v Ireland | Rajiv Gandhi International Cricket Stadium, Dehra Dun | 2018/19 |
| 2-81 | Zahir Khan | Afghanistan v Zimbabwe | Sheikh Zayed Stadium, Abu Dhabi | 2020/21 |
| 5-79 | Nijat Masood | Afghanistan v Bangladesh | Shere Bangla National Stadium, Mirpur | 2023 |
| 2-76 | Nijat Masood | Afghanistan v Sri Lanka | Sinhalese Sports Club Ground, Colombo | 2023/24 |
| 1-75 | Mujeeb Zadran | Afghanistan v India | M Chinnaswamy Stadium, Bangalore | 2018 |
| 6-75 | Hamza Hotak | Afghanistan v Zimbabwe | Sheikh Zayed Stadium, Abu Dhabi | 2020/21 |
| 5-74 | Hamza Hotak | Afghanistan v West Indies | Bharat Ratna Shri Atal Bihari Vajpayee Ekana Cricket Stadium, Lucknow | 2019/20 |
| 3-73 | Hamza Hotak | Afghanistan v Zimbabwe | Sheikh Zayed Stadium, Abu Dhabi | 2020/21 |
| 1-67 | Zahir Khan | Afghanistan v Ireland | Tolerance Oval, Abu Dhabi | 2023/24 |
| 1-66 | Azmatullah Omarzai | Afghanistan v Zimbabwe | Queens Sports Club, Bulawayo | 2024/25 |
| 2-66 | Waqar Salamkheil | Afghanistan v Ireland | Rajiv Gandhi International Cricket Stadium, Dehra Dun | 2018/19 |
| 7-66 | Rashid Khan | Afghanistan v Zimbabwe | Queens Sports Club, Bulawayo | 2024/25 |
