| Runs |
Out of |
4s |
6s |
| 42 | 70 | 9 | 1 | | Ibrahim Zadran | Afghanistan v Uganda | Guyana National Stadium, Providence | 2024 |
| 50 | 80 | 5 | 5 | | Rahmanullah Gurbaz | Afghanistan v New Zealand | Guyana National Stadium, Providence | 2024 |
| 42 | 68 | 6 | 3 | | Mohammad Shahzad | Afghanistan v Hong Kong | Zohur Ahmed Chowdhury Stadium, Chittagong | 2013/14 |
| 42 | 73 | 6 | 3 | | Najibullah Zadaran | Afghanistan v New Zealand | Sheikh Zayed Stadium, Abu Dhabi | 2021/22 |
| 38 | 44 | 5 | 3 | | Gulbadeen Naib | Afghanistan v England | R Premadasa Stadium, Colombo | 2012/13 |
| 38 | 51* | 5 | 3 | | Shafiqullah Shinwari | Afghanistan v Hong Kong | Zohur Ahmed Chowdhury Stadium, Chittagong | 2013/14 |
| 38 | 61 | 5 | 3 | | Mohammad Shahzad | Afghanistan v Scotland | Vidarbha Cricket Association Stadium, Nagpur | 2015/16 |
| 34 | 40 | 7 | 1 | | Mohammad Shahzad | Afghanistan v Zimbabwe | Vidarbha Cricket Association Stadium, Nagpur | 2015/16 |
| 42 | 44 | 3 | 5 | | Mohammad Shahzad | Afghanistan v South Africa | Wankhede Stadium, Mumbai | 2015/16 |
| 38 | 59 | 5 | 3 | | Najibullah Zadaran | Afghanistan v Scotland | Sharjah Cricket Association Stadium, Sharjah | 2021/22 |
| 40 | 76 | 4 | 4 | | Rahmanullah Gurbaz | Afghanistan v Uganda | Guyana National Stadium, Providence | 2024 |
| 40 | 60 | 4 | 4 | | Rahmanullah Gurbaz | Afghanistan v Australia | Arnos Vale Playing Field, Kingstown | 2024 |
| 36 | 62 | 3 | 4 | | Asghar Stanikzai | Afghanistan v Sri Lanka | Eden Gardens, Kolkata | 2015/16 |
| 36 | 48* | 3 | 4 | | Rashid Khan | Afghanistan v Australia | Adelaide Oval, Adelaide | 2022/23 |
| 28 | 41 | 4 | 2 | | Mohammad Shahzad | Afghanistan v Hong Kong | Vidarbha Cricket Association Stadium, Nagpur | 2015/16 |
| 28 | 52 | 4 | 2 | | Mohammad Nabi | Afghanistan v Zimbabwe | Vidarbha Cricket Association Stadium, Nagpur | 2015/16 |
| 28 | 35* | 4 | 2 | | Shafiqullah Shinwari | Afghanistan v England | Feroz Shah Kotla, Delhi | 2015/16 |
| 30 | 44 | 3 | 3 | | Hazratullah Zazai | Afghanistan v Scotland | Sharjah Cricket Association Stadium, Sharjah | 2021/22 |
| 28 | 33 | 4 | 2 | | Hazratullah Zazai | Afghanistan v Namibia | Sheikh Zayed Stadium, Abu Dhabi | 2021/22 |
| 26 | 32* | 5 | 1 | | Mohammad Nabi | Afghanistan v Namibia | Sheikh Zayed Stadium, Abu Dhabi | 2021/22 |
| 28 | 49* | 4 | 2 | | Gulbadeen Naib | Afghanistan v Papua New Guinea | Brian Lara Stadium, Tarouba | 2024 |
| 26 | 38 | 5 | 1 | | Ibrahim Zadran | Afghanistan v West Indies | Daren Sammy National Cricket Stadium, Gros Islet | 2024 |
| 24 | 51 | 6 | 0 | | Ibrahim Zadran | Afghanistan v Australia | Arnos Vale Playing Field, Kingstown | 2024 |
| 22 | 49 | 4 | 1 | | Asghar Stanikzai | Afghanistan v Nepal | Zohur Ahmed Chowdhury Stadium, Chittagong | 2013/14 |
| 22 | 43 | 4 | 1 | | Samiullah Shenwari | Afghanistan v Zimbabwe | Vidarbha Cricket Association Stadium, Nagpur | 2015/16 |
| 24 | 31 | 3 | 2 | | Samiullah Shenwari | Afghanistan v Sri Lanka | Eden Gardens, Kolkata | 2015/16 |
| 22 | 48* | 4 | 1 | | Najibullah Zadaran | Afghanistan v West Indies | Vidarbha Cricket Association Stadium, Nagpur | 2015/16 |
| 28 | 46 | 1 | 4 | | Rahmanullah Gurbaz | Afghanistan v Scotland | Sharjah Cricket Association Stadium, Sharjah | 2021/22 |
| 22 | 35* | 4 | 1 | | Gulbadeen Naib | Afghanistan v Pakistan | Dubai Sports City Stadium, Dubai | 2021/22 |
| 20 | 35* | 5 | 0 | | Mohammad Nabi | Afghanistan v Pakistan | Dubai Sports City Stadium, Dubai | 2021/22 |
| 24 | 45 | 3 | 2 | | Mohammad Shahzad | Afghanistan v Namibia | Sheikh Zayed Stadium, Abu Dhabi | 2021/22 |
| 24 | 42* | 3 | 2 | | Karim Janat | Afghanistan v India | Sheikh Zayed Stadium, Abu Dhabi | 2021/22 |
| 24 | 39 | 3 | 2 | | Gulbadeen Naib | Afghanistan v Australia | Adelaide Oval, Adelaide | 2022/23 |
| 24 | 44 | 3 | 2 | | Ibrahim Zadran | Afghanistan v New Zealand | Guyana National Stadium, Providence | 2024 |
