| Wkt |
| 2 | 149 | GM Smith (100*) & WW Hinds (61) | Derbyshire v Yorkshire | Headingley, Leeds | 2008 |
| 1 | 148 | HRC Came (56) & TA Wood (110*) | Derbyshire v Leicestershire | The Incora County Ground, Derby | 2023 |
| 2 | 141 | LE Bosman (94) & CF Hughes (65) | Derbyshire v Yorkshire | Headingley, Leeds | 2010 |
| 1 | 135 | LM Reece (51) & BA Godleman (92) | Derbyshire v Worcestershire | The Pattonair County Ground, Derby | 2019 |
| 2 | 126 | CS MacLeod (104) & WL Madsen (50*) | Derbyshire v Northamptonshire | County Ground, Northampton | 2018 |
| 3 | 115 | GM Smith (52) & WW Hinds (66) | Derbyshire v Nottinghamshire | County Ground, Derby | 2009 |
| 1 | 115 | AHT Donald (85) & CP Jewell (31) | Derbyshire v Yorkshire | Queen's Park, Chesterfield | 2025 |
| 1 | 114 | DL Lloyd (41) & AHT Donald (84) | Derbyshire v Yorkshire | Headingley, Leeds | 2024 |
| 4 | 114 | CP Jewell (71) & SR Patel (83*) | Derbyshire v Northamptonshire | The Central Co-op County Ground, Derby | 2025 |
| 2 | 112 | BA Godleman (57) & WL Madsen (69) | Derbyshire v Lancashire | Emirates Old Trafford, Manchester | 2019 |
| 2 | 112 | LM Reece (53) & WL Madsen (61) | Derbyshire v Nottinghamshire | Trent Bridge, Nottingham | 2023 |
| 1 | 112 | AHT Donald (71) & CP Jewell (39) | Derbyshire v Northamptonshire | County Ground, Northampton | 2025 |
| 1 | 109 | TA Wood (67) & BA Godleman (49) | Derbyshire v Yorkshire | Emerald Headingley Cricket Stadium, Leeds | 2020 |
| 4 | 103 | WW Hinds (72*) & DJ Pipe (44) | Derbyshire v Lancashire | Old Trafford, Manchester | 2008 |
| 2 | 103 | WJ Durston (86) & CF Hughes (65) | Derbyshire v Lancashire | County Ground, Derby | 2011 |
| 4 | 103 | GD Cross (54) & WL Madsen (65) | Derbyshire v Nottinghamshire | Trent Bridge, Nottingham | 2014 |
| 4 | 102 | WL Madsen (43) & SR Patel (64) | Derbyshire v Leicestershire | Edgbaston, Birmingham | 2024 |
| 3 | 100 | HRC Came (56) & JL du Plooy (92) | Derbyshire v Lancashire | The Incora County Ground, Derby | 2021 |
| 1 | 99 | Shan Masood (73) & LM Reece (39) | Derbyshire v Leicestershire | The Incora County Ground, Derby | 2022 |
| 3 | 99 | Shan Masood (75) & WL Madsen (70) | Derbyshire v Lancashire | The Incora County Ground, Derby | 2022 |
| 1 | 98 | CF Hughes (46) & WJ Durston (50*) | Derbyshire v Nottinghamshire | Trent Bridge, Nottingham | 2013 |
| 4 | 97* | CF Hughes (43*) & WL Madsen (59*) | Derbyshire v Worcestershire | County Ground, New Road, Worcester | 2016 |
| 2 | 97 | Shan Masood (31) & WL Madsen (100*) | Derbyshire v Durham | The Incora County Ground, Derby | 2022 |
| 2 | 95 | CJL Rogers (50) & GT Park (50) | Derbyshire v Durham | Riverside Ground, Chester-le-Street | 2009 |
| 3 | 95 | Shan Masood (57) & WL Madsen (73) | Derbyshire v Northamptonshire | The Incora County Ground, Derby | 2022 |
| 3 | 95 | TA Wood (37) & WL Madsen (109*) | Derbyshire v Leicestershire | Uptonsteel County Ground, Leicester | 2023 |
| 1 | 95 | LM Reece (57) & Haider Ali (48) | Derbyshire v Warwickshire | Edgbaston, Birmingham | 2023 |
| 2 | 94 | WJ Durston (83) & S Chanderpaul (38) | Derbyshire v Leicestershire | Grace Road, Leicester | 2013 |
| 2 | 94* | HD Rutherford (71*) & NT Broom (25*) | Derbyshire v Lancashire | Emirates Old Trafford, Manchester | 2016 |
| 1 | 94 | DL Lloyd (33*) & AHT Donald (68) | Derbyshire v Northamptonshire | The Incora County Ground, Derby | 2024 |
