| Runs |
Wkts |
| 461 | 10 | Northamptonshire v Derbyshire | County Ground, Northampton | 2025 |
| 449 | 8 | Nottinghamshire v Derbyshire | Trent Bridge, Nottingham | 2017 |
| 424 | 12 | Warwickshire v Derbyshire | Edgbaston, Birmingham | 2015 |
| 421 | 11 | Lancashire v Derbyshire | Emirates Old Trafford, Manchester | 2022 |
| 416 | 15 | Derbyshire v Worcestershire | The Incora County Ground, Derby | 2023 |
| 415 | 14 | Lancashire v Derbyshire | Emirates Old Trafford, Manchester | 2014 |
| 410 | 11 | Warwickshire v Derbyshire | Edgbaston, Birmingham | 2023 |
| 408 | 13 | Derbyshire v Leicestershire | Queen's Park, Chesterfield | 2010 |
| 406 | 17 | Derbyshire v Lancashire | The Central Co-op County Ground, Derby | 2025 |
| 401 | 9 | Derbyshire v Yorkshire | Queen's Park, Chesterfield | 2025 |
| 400 | 15 | Nottinghamshire v Derbyshire | Trent Bridge, Nottingham | 2022 |
| 397 | 18 | Derbyshire v Hampshire | The 3aaa County Ground, Derby | 2017 |
| 397 | 14 | Derbyshire v Warwickshire | The Incora County Ground, Derby | 2022 |
| 395 | 16 | Leicestershire v Derbyshire | Uptonsteel County Ground, Leicester | 2021 |
| 393 | 12 | Yorkshire v Derbyshire | Headingley, Leeds | 2005 |
| 393 | 8 | Derbyshire v Lancashire | The Incora County Ground, Derby | 2021 |
| 393 | 8 | Derbyshire v Leicestershire | Edgbaston, Birmingham | 2025 |
| 392 | 14 | Northamptonshire v Derbyshire | County Ground, Northampton | 2016 |
| 391 | 12 | Northamptonshire v Derbyshire | County Ground, Northampton | 2018 |
| 391 | 7 | Durham v Derbyshire | Emirates Riverside, Chester-le-Street | 2020 |
| 391 | 13 | Derbyshire v Leicestershire | The Incora County Ground, Derby | 2023 |
| 390 | 11 | Worcestershire v Derbyshire | County Ground, New Road, Worcester | 2014 |
| 387 | 14 | Derbyshire v Lancashire | The 3aaa County Ground, Derby | 2017 |
| 387 | 10 | Derbyshire v Durham | The Incora County Ground, Derby | 2022 |
| 385 | 11 | Nottinghamshire v Derbyshire | Trent Bridge, Nottingham | 2010 |
| 385 | 12 | Nottinghamshire v Derbyshire | Trent Bridge, Nottingham | 2014 |
| 384 | 12 | Derbyshire v Lancashire | County Ground, Derby | 2009 |
| 383 | 12 | Northamptonshire v Derbyshire | County Ground, Northampton | 2014 |
| 383 | 12 | Nottinghamshire v Derbyshire | Trent Bridge, Nottingham | 2020 |
| 382 | 12 | Derbyshire v Warwickshire | The 3aaa County Ground, Derby | 2014 |
| 382 | 10 | Derbyshire v Northamptonshire | The Central Co-op County Ground, Derby | 2025 |
