| 244 | PP Shaw | v Somerset | County Ground, Northampton | 2023 | a30124 |
| 172* | W Larkins | v Warwickshire | Wardown Park, Luton | 1983 | a3705 |
| 167 | DJ Willey | v Warwickshire | Edgbaston, Birmingham | 2013 | a22806 |
| 161 | DJG Sales | v Yorkshire | County Ground, Northampton | 2006 | a17437 |
| 158 | W Larkins | v Worcestershire | Wardown Park, Luton | 1982 | a3416 |
| 153* | RJ Bailey | v Pakistan A | County Ground, Northampton | 1997 | a10661 |
| 146* | JJ Cobb | v Pakistanis | County Ground, Northampton | 2019 | a27344 |
| 145 | RJ Bailey | v Staffordshire | Lichfield Road, Stone | 1991 | a7098 |
| 136 | SA Zaib | v Essex | County Ground, Northampton | 2022 | a29340 |
| 134 | RJ Bailey | v Gloucestershire | County Ground, Northampton | 1987 | a5225 |
| 134 | RI Keogh | v Durham | County Ground, Northampton | 2016 | a24831 |
| 133* | DJG Sales | v Nottinghamshire | County Ground, Northampton | 2003 | a15079 |
| 132 | W Larkins | v Warwickshire | Edgbaston, Birmingham | 1982 | a3321 |
| 132* | AJ Lamb | v Surrey | Woodbridge Road, Guildford | 1985 | a4563 |
| 132* | A Fordham | v Leicestershire | County Ground, Northampton | 1991 | a7119 |
| 132 | A Fordham | v Nottinghamshire | Trent Bridge, Nottingham | 1995 | a9331 |
| 132 | U Afzaal | v Yorkshire | Headingley, Leeds | 2007 | a18277 |
| 131 | Mushtaq Mohammad | v Minor Counties East | Trentham Road, Stoke-on-Trent | 1976 | a1674 |
| 131 | TW Roberts | v Nottinghamshire | Trent Bridge, Nottingham | 2003 | a15284 |
| 131 | EN Gay | v Lancashire | Stanley Park, Blackpool | 2022 | a29398 |
| 130 | G Cook | v Shropshire | St Georges Recreation Ground, Telford | 1985 | a4498 |
| 130 | A Fordham | v Staffordshire | County Ground, Northampton | 1990 | a6617 |
| 129* | AJ Lamb | v Middlesex | Uxbridge Cricket Club Ground, Uxbridge | 1994 | a8712 |
| 128 | RK Kleinveldt | v Nottinghamshire | Trent Bridge, Nottingham | 2016 | a24752 |
| 127* | AJ Lamb | v Worcestershire | County Ground, New Road, Worcester | 1981 | a2999 |
| 126 | W Larkins | v Scotland | Titwood, Glasgow | 1982 | a3281 |
| 126 | W Larkins | v Surrey | Woodbridge Road, Guildford | 1985 | a4563 |
| 126* | AJ Lamb | v Kent | St Lawrence Ground, Canterbury | 1987 | a5280 |
| 125* | AJ Lamb | v Hampshire | County Ground, Northampton | 1985 | a4382 |
| 125* | RJ Bailey | v Derbyshire | County Ground, Derby | 1987 | a5199 |
| 125* | PP Shaw | v Durham | Seat Unique Riverside Ground, Chester-le-Street | 2023 | a30133 |
| 124* | AJ Lamb | v Essex | County Ground, Chelmsford | 1993 | a8123 |
| 124* | MB Loye | v Northamptonshire Cricket Board | County Ground, Northampton | 2001 | a13573 |
| 123 | MB Loye | v Sri Lankans | County Ground, Northampton | 2002 | a14374 |
| 123 | MEK Hussey | v Scotland | County Ground, Northampton | 2003 | a15244 |
| 122 | MB Loye | v Somerset | Wardown Park, Luton | 1993 | a8112 |
| 122* | U Afzaal | v Middlesex | County Ground, Northampton | 2005 | a16667 |
| 121* | W Larkins | v Essex | County Ground, Chelmsford | 1987 | a5349 |
| 121 | DJ Capel | v Glamorgan | County Ground, Northampton | 1990 | a6586 |
| 121 | NJ O'Brien | v Hampshire | The Rose Bowl, Southampton | 2011 | a21377 |
| 121 | BM Duckett | v Yorkshire | North Marine Road, Scarborough | 2016 | a24784 |
| 120 | AJ Lamb | v Sussex | County Ground, Northampton | 1992 | a7639 |
| 119* | KM Curran | v Kent | St Lawrence Ground, Canterbury | 1995 | a9342 |
| 118* | RJ Bailey | v Worcestershire | County Ground, Northampton | 1986 | a4879 |
| 117 | PA Jaques | v Hampshire | County Ground, Northampton | 2003 | a15196 |
| 117 | U Afzaal | v Worcestershire | County Ground, New Road, Worcester | 2005 | a16772 |
| 117 | JJG Sales | v Durham | Banks Homes Riverside, Chester-le-Street | 2025 | a31822 |
| 116 | AJ Lamb | v Nottinghamshire | Trent Bridge, Nottingham | 1987 | a5233 |
| 116* | DJG Sales | v Nottinghamshire | County Ground, Northampton | 2007 | a18204 |
| 115* | HM Ackerman | v Kent | Crabble Athletic Ground, Dover | 1970 | a346 |
| 115 | DJ Capel | v Sussex | Wellingborough School Ground, Wellingborough | 1990 | a6661 |
| 115* | RJ Bailey | v Nottinghamshire | County Ground, Northampton | 1996 | a9837 |
| 114* | G Cook | v Surrey | County Ground, Northampton | 1979 | a2488 |
| 114* | MEK Hussey | v Glamorgan | Sophia Gardens, Cardiff | 2001 | a13464 |
| 113 | DJ Willey | v Essex | County Ground, Northampton | 2014 | a23509 |
| 112 | DJ Capel | v Surrey | The Foster's Oval, Kennington | 1996 | a10042 |
| 112 | MB Loye | v Zimbabweans | County Ground, Northampton | 2000 | a12817 |
| 112* | MEK Hussey | v Durham | Riverside Ground, Chester-le-Street | 2003 | a15206 |
| 112 | TW Roberts | v Warwickshire | Edgbaston, Birmingham | 2004 | a15973 |
| 112 | RS Vasconcelos | v Yorkshire | County Ground, Northampton | 2019 | a27351 |
| 112 | TAI Taylor | v Gloucestershire | College Ground, Cheltenham | 2023 | a30111 |
| 111 | W Larkins | v Leicestershire | Wellingborough School Ground, Wellingborough | 1979 | a2519 |
| 111 | G Cook | v Derbyshire | Lord's Cricket Ground, St John's Wood | 1981 | a3109 |
| 111 | W Larkins | v Scotland | County Ground, Northampton | 1990 | a6537 |
| 111 | A Fordham | v Durham | Park Drive, Hartlepool | 1994 | a8663 |
| 111* | ML Love | v Middlesex | County Ground, Northampton | 2005 | a16667 |
| 111 | RA White | v Warwickshire | County Ground, Northampton | 2008 | a18960 |
| 110 | MEK Hussey | v Middlesex | Lord's Cricket Ground, St John's Wood | 2002 | a14452 |
| 109 | DS Steele | v Cambridgeshire | The Avenue Sports Club Ground, March | 1975 | a1447 |
| 109 | W Larkins | v Gloucestershire | County Ground, Northampton | 1990 | a6703 |
| 109* | RJ Bailey | v Hampshire | County Ground, Southampton | 1992 | a7518 |
| 109 | RR Montgomerie | v Nottinghamshire | Trent Bridge, Nottingham | 1995 | a9331 |
| 109 | RE Levi | v Derbyshire | The 3aaa County Ground, Derby | 2017 | a25500 |
| 109* | AG Wakely | v Lancashire | Aigburth, Liverpool | 2017 | a25536 |
| 108 | W Larkins | v Warwickshire | Edgbaston, Birmingham | 1980 | a2632 |
| 108 | G Cook | v Gloucestershire | County Ground, Northampton | 1987 | a5225 |
| 108 | W Larkins | v Essex | County Ground, Northampton | 1991 | a7161 |
| 108* | AJ Lamb | v Lancashire | County Ground, Northampton | 1992 | a7546 |
| 108 | A Fordham | v Scotland | County Ground, Northampton | 1995 | a9238 |
| 108* | MB Loye | v Middlesex | County Ground, Northampton | 1998 | a11245 |
| 108* | U Afzaal | v Durham | County Ground, Northampton | 2006 | a17551 |
| 107 | P Willey | v Warwickshire | Edgbaston, Birmingham | 1975 | a1458 |
| 107 | P Willey | v Hampshire | London Road, Tring | 1976 | a1694 |
| 107* | W Larkins | v Surrey | London Road, Tring | 1978 | a2224 |
| 107 | ML Hayden | v Essex | County Ground, Northampton | 1999 | a12008 |
| 107 | PA Jaques | v Lancashire | County Ground, Northampton | 2003 | a15334 |
| 107 | SD Peters | v Yorkshire | Headingley, Leeds | 2007 | a18277 |
| 107 | RI Newton | v Worcestershire | County Ground, Northampton | 2017 | a25523 |
| 107 | LD McManus | v Derbyshire | County Ground, Northampton | 2022 | a29416 |
| 106* | AJ Lamb | v Leicestershire | Grace Road, Leicester | 1983 | a3639 |
| 106 | AJ Lamb | v Leicestershire | County Ground, Northampton | 1986 | a4828 |
| 106* | RJ Bailey | v Surrey | County Ground, Northampton | 1989 | a6077 |
| 106 | RS Vasconcelos | v Glamorgan | Sophia Gardens, Cardiff | 2023 | a30170 |
| 105 | W Larkins | v Scotland | County Ground, Northampton | 1985 | a4415 |
| 105* | RJ Bailey | v Kent | County Ground, Northampton | 1996 | a9877 |
| 105* | KJ Coetzer | v Worcestershire | County Ground, Northampton | 2013 | a22707 |
| 104* | P Willey | v Yorkshire | Park Avenue Cricket Ground, Bradford | 1976 | a1692 |
| 104* | AJ Lamb | v Essex | County Ground, Chelmsford | 1982 | a3461 |
| 104 | W Larkins | v Lancashire | County Ground, Northampton | 1990 | a6686 |
| 104 | DJG Sales | v Pakistanis | County Ground, Northampton | 2003 | a15161 |
| 104* | AJ Hall | v Warwickshire | County Ground, Northampton | 2009 | a19919 |
| 104 | JJ Cobb | v Derbyshire | The 3aaa County Ground, Derby | 2015 | a24178 |
| 104 | RS Vasconcelos | v Glamorgan | County Ground, Northampton | 2022 | a29365 |
| 104* | WA Young | v Worcestershire | County Ground, Northampton | 2022 | a29388 |
| 104 | RS Vasconcelos | v Lancashire | Stanley Park, Blackpool | 2022 | a29398 |
| 103* | RJ Bailey | v Middlesex | London Road, Tring | 1985 | a4507 |
| 103 | AJ Lamb | v Suffolk | The Victory Ground, Bury St Edmunds | 1989 | a6117 |
| 103 | A Fordham | v Scotland | Lochside Park, Forfar | 1992 | a7498 |
| 103 | MEK Hussey | v Derbyshire | County Ground, Derby | 2003 | a15263 |
| 103* | SD Peters | v Ireland | County Ground, Northampton | 2008 | a18975 |
| 102 | P Willey | v Sussex | County Ground, Hove | 1971 | a472 |
| 102* | A Tait | v Warwickshire | Baker Perkins Sports Ground, Peterborough | 1974 | a1193 |
| 102 | P Willey | v Leicestershire | Grace Road, Leicester | 1976 | a1733 |
| 102 | W Larkins | v Gloucestershire | County Ground, Northampton | 1983 | a3688 |
| 102 | JW Cook | v Lancashire | County Ground, Northampton | 2002 | a14396 |
| 102 | M van Jaarsveld | v New Zealanders | County Ground, Northampton | 2004 | a15947 |
| 102 | AG Wakely | v Kent | The Nevill Ground, Tunbridge Wells | 2013 | a22661 |
| 102 | RI Keogh | v Leicestershire | Fischer County Ground, Grace Road, Leicester | 2019 | a27358 |
| 101* | P Willey | v Leicestershire | Wellingborough School Ground, Wellingborough | 1979 | a2519 |
| 101 | AJ Lamb | v Sussex | County Ground, Hove | 1979 | a2530 |
| 101 | W Larkins | v Gloucestershire | Batsford Road, Moreton-in-Marsh | 1989 | a6189 |
| 101 | DJ Capel | v Nottinghamshire | County Ground, Northampton | 1990 | a6642 |
| 101 | A Fordham | v Australians | County Ground, Northampton | 1993 | a8042 |
| 101* | MB Loye | v Surrey | Whitgift School, Croydon | 2002 | a14433 |
| 101 | RA White | v Glamorgan | County Ground, Northampton | 2004 | a15987 |
| 100* | RJ Warren | v Ireland | County Ground, Northampton | 1994 | a8686 |
| 100 | MH Wessels | v Surrey | The Brit Oval, Kennington | 2008 | a19112 |
| 100 | TAI Taylor | v Worcestershire | County Ground, Northampton | 2023 | a30149 |
| 100 | RI Keogh | v Glamorgan | Sophia Gardens, Cardiff | 2023 | a30170 |
