| 161 | A Lyth | for Yorkshire | Headingley, Leeds | 2017 | tt6433 |
| 136 | JM Clarke | for Nottinghamshire | County Ground, Northampton | 2021 | tt9659 |
| 131 | IR Bell | for Warwickshire | Edgbaston, Birmingham | 2018 | tt7060 |
| 119 | AJ Hose | for Warwickshire | Edgbaston, Birmingham | 2020 | tt9018 |
| 119 | PR Stirling | for Warwickshire | Edgbaston, Birmingham | 2022 | tt10830 |
| 116* | GA Hick | for Worcestershire | Wardown Park, Luton | 2004 | tt77 |
| 113* | DT Christian | for Nottinghamshire | County Ground, Northampton | 2018 | tt7017 |
| 110 | GA Hick | for Worcestershire | Chester Road North, Kidderminster | 2007 | tt678 |
| 108* | CA Lynn | for Hampshire | Edgbaston, Birmingham | 2025 | tt15747 |
| 105 | GC Smith | for Somerset | County Ground, Taunton | 2005 | tt216 |
| 104 | CS MacLeod | for Derbyshire | County Ground, Northampton | 2018 | tt7052 |
| 104 | RK Patel | for Leicestershire | County Ground, Northampton | 2024 | tt13841 |
| 103* | JP Inglis | for Leicestershire | County Ground, Northampton | 2021 | tt9718 |
| 102 | MJ Guptill | for Worcestershire | County Ground, Northampton | 2018 | tt7066 |
| 102* | G Clark | for Durham | County Ground, Northampton | 2023 | tt12202 |
| 101* | HH Gibbs | for Yorkshire | County Ground, Northampton | 2010 | tt1821 |
| 101 | SJ Croft | for Lancashire | County Ground, Northampton | 2023 | tt12348 |
| 101* | AZ Lees | for Durham | Banks Homes Riverside, Chester-le-Street | 2025 | tt15513 |
| 98 | HH Gibbs | for Glamorgan | County Ground, Northampton | 2008 | tt964 |
| 97 | JL Langer | for Somerset | County Ground, Taunton | 2006 | tt402 |
| 94* | MA Hardinges | for Gloucestershire | County Ground, Bristol | 2006 | tt428 |
| 93 | SR Hain | for Warwickshire | County Ground, Northampton | 2024 | tt13977 |
| 90 | MM Ali | for Worcestershire | County Ground, Northampton | 2015 | tt4943 |
| 88 | DL Maddy | for Warwickshire | Edgbaston, Birmingham | 2010 | tt1728 |
| 88 | KK Jennings | for Durham | Edgbaston, Birmingham | 2016 | tt5882 |
| 88 | Kashif Ali | for Worcestershire | County Ground, Northampton | 2025 | tt15411 |
| 87 | ST Jayasuriya | for Worcestershire | County Ground, New Road, Worcester | 2010 | tt1803 |
| 85 | CN Ackermann | for Leicestershire | Uptonsteel County Ground, Leicester | 2022 | tt11054 |
| 83* | Z de Bruyn | for Somerset | County Ground, Northampton | 2009 | tt1277 |
| 83* | SR Patel | for Derbyshire | The Central Co-op County Ground, Derby | 2025 | tt15185 |
| 80* | MW Goodwin | for Sussex | Edgbaston, Birmingham | 2009 | tt1350 |
| 80* | JW Hastings | for Durham | Emirates Durham International Cricket Ground, Chester-le-Street | 2014 | tt4468 |
| 80 | PD Salt | for Lancashire | County Ground, Northampton | 2025 | tt15389 |
| 79 | MJ Cosgrove | for Leicestershire | County Ground, Northampton | 2017 | tt6409 |
| 79 | DJ Willey | for Yorkshire | County Ground, Northampton | 2018 | tt7144 |
| 79 | G Clark | for Durham | Banks Homes Riverside, Chester-le-Street | 2025 | tt15513 |
| 77 | RK Oliver | for Worcestershire | County Ground, New Road, Worcester | 2014 | tt4360 |
| 77* | WJ Durston | for Derbyshire | County Ground, Northampton | 2015 | tt4951 |
| 77 | R McLaren | for Lancashire | County Ground, Northampton | 2017 | tt6381 |
| 77 | BA Godleman | for Derbyshire | The 3aaa County Ground, Derby | 2018 | tt7105 |
| 76 | ME Trescothick | for Somerset | County Ground, Taunton | 2007 | tt653 |
| 75* | LM Reece | for Derbyshire | County Ground, Northampton | 2017 | tt6310 |
| 75* | AL Davies | for Lancashire | County Ground, Northampton | 2019 | tt8055 |
| 75 | T Banton | for Somerset | County Ground, Northampton | 2024 | tt14145 |
