| Runs |
Out of |
4s |
6s |
| 96 | 116 | 18 | 4 | | TT Beaumont | England Women v South Africa Women | The Cooper Associates County Ground, Taunton | 2018 |
| 90 | 124 | 15 | 5 | | DN Wyatt | England Women v India Women | Brabourne Stadium, Mumbai | 2017/18 |
| 76 | 108* | 13 | 4 | | HC Knight | England Women v Thailand Women | Manuka Oval, Canberra | 2019/20 |
| 66 | 78 | 15 | 1 | | DN Wyatt | England Women v South Africa Women | Willowmoore Park Main Oval, Benoni | 2024/25 |
| 64 | 100 | 13 | 2 | | DN Wyatt | England Women v Australia Women | Manuka Oval, Canberra | 2017/18 |
| 58 | 92* | 13 | 1 | | CM Edwards | England Women v Australia Women | Blundstone Arena, Hobart | 2013/14 |
| 62 | 89 | 11 | 3 | | AE Jones | England Women v Pakistan Women | Kinrara Academy Oval, Kuala Lumpur | 2019/20 |
| 58 | 97 | 13 | 1 | | TT Beaumont | England Women v New Zealand Women | The Cloudfm County Ground, Chelmsford | 2021 |
| 60 | 91 | 12 | 2 | | ME Bouchier | England Women v New Zealand Women | Cello Basin Reserve, Wellington | 2023/24 |
| 54 | 89* | 12 | 1 | | DN Wyatt | England Women v India Women | The Cloudfm County Ground, Chelmsford | 2021 |
| 54 | 81* | 12 | 1 | | NR Sciver | England Women v Pakistan Women | PPC Newlands, Cape Town | 2022/23 |
| 52 | 76 | 13 | 0 | | DN Wyatt | England Women v Australia Women | The Kia Oval, Kennington | 2023 |
| 52 | 77 | 13 | 0 | | NR Sciver | England Women v India Women | Wankhede Stadium, Mumbai | 2023/24 |
| 54 | 87 | 12 | 1 | | DN Wyatt | England Women v Pakistan Women | Headingley, Leeds | 2024 |
| 52 | 64 | 10 | 2 | | CM Edwards | England Women v South Africa Women | County Ground, Taunton | 2007 |
| 52 | 82 | 10 | 2 | | TT Beaumont | England Women v Pakistan Women | Brightside Ground, Bristol | 2016 |
| 52 | 68* | 10 | 2 | | NR Sciver | England Women v Australia Women | Brabourne Stadium, Mumbai | 2017/18 |
| 50 | 71 | 11 | 1 | | ME Bouchier | England Women v New Zealand Women | Saxton Oval, Nelson | 2023/24 |
| 50 | 76 | 11 | 1 | | DN Wyatt | England Women v New Zealand Women | Utilita Bowl, Southampton | 2024 |
| 48 | 58 | 12 | 0 | | BF Smith | England Women v Ireland Women | Castle Avenue, Dublin | 2024 |
| 48 | 62* | 12 | 0 | | ME Bouchier | England Women v Scotland Women | Sharjah Cricket Association Stadium, Sharjah | 2024/25 |
| 48 | 81* | 12 | 0 | | SIR Dunkley | England Women v West Indies Women | Spitfire Ground, St Lawrence, Canterbury | 2025 |
| 44 | 60 | 11 | 0 | | CM Edwards | England Women v New Zealand Women | North Parade, Bath | 2007 |
| 44 | 75* | 11 | 0 | | SC Taylor | England Women v Sri Lanka Women | County Ground, Taunton | 2009 |
| 44 | 48 | 11 | 0 | | LA Marsh | England Women v New Zealand Women | Seddon Park, Hamilton | 2011/12 |
| 44 | 80* | 11 | 0 | | LS Greenway | England Women v Australia Women | The Ageas Bowl, Southampton | 2013 |
| 44 | 80 | 11 | 0 | | CM Edwards | England Women v Bangladesh Women | Sylhet Stadium, Sylhet | 2013/14 |
| 44 | 75* | 11 | 0 | | CM Edwards | England Women v South Africa Women | County Ground, Northampton | 2014 |
| 44 | 74* | 11 | 0 | | SJ Taylor | England Women v South Africa Women | Boland Park, Paarl | 2015/16 |
| 46 | 74 | 10 | 1 | | L Winfield | England Women v Pakistan Women | Brightside Ground, Bristol | 2016 |
| 50 | 78 | 8 | 3 | | HC Knight | England Women v Australia Women | Manuka Oval, Canberra | 2019/20 |
| 46 | 51 | 10 | 1 | | AR Capsey | England Women v Ireland Women | Eurolux Boland Park, Paarl | 2022/23 |
| 46 | 53* | 10 | 1 | | DN Wyatt | England Women v South Africa Women | SuperSport Park, Centurion | 2024/25 |
| 40 | 69 | 10 | 0 | | SJ Taylor | England Women v India Women | St Lawrence Ground, Canterbury | 2012 |
| 40 | 62* | 10 | 0 | | CM Edwards | England Women v South Africa Women | The Essex County Ground, Chelmsford | 2014 |
| 42 | 74 | 9 | 1 | | L Winfield | England Women v South Africa Women | Edgbaston, Birmingham | 2014 |
| 40 | 60 | 10 | 0 | | SJ Taylor | England Women v South Africa Women | Bidvest Wanderers Stadium, Johannesburg | 2015/16 |
| 40 | 77* | 10 | 0 | | CM Edwards | England Women v Pakistan Women | MA Chidambaram Stadium, Chepauk, Chennai | 2015/16 |
| 42 | 63 | 9 | 1 | | L Winfield | England Women v Pakistan Women | The Essex County Ground, Chelmsford | 2016 |
| 40 | 49* | 10 | 0 | | NR Sciver | England Women v Sri Lanka Women | P Sara Oval, Colombo | 2018/19 |
| 40 | 81 | 10 | 0 | | DN Wyatt | England Women v West Indies Women | County Ground, Northampton | 2019 |
| 40 | 53 | 10 | 0 | | AE Jones | England Women v Pakistan Women | Kinrara Academy Oval, Kuala Lumpur | 2019/20 |
| 44 | 55 | 8 | 2 | | DN Wyatt | England Women v Pakistan Women | Kinrara Academy Oval, Kuala Lumpur | 2019/20 |
| 44 | 67 | 8 | 2 | | HC Knight | England Women v India Women | Manuka Oval, Canberra | 2019/20 |
| 42 | 62 | 9 | 1 | | TT Beaumont | England Women v West Indies Women | The Incora County Ground, Derby | 2020 |
| 42 | 82 | 9 | 1 | | NR Sciver | England Women v West Indies Women | The Incora County Ground, Derby | 2020 |
| 44 | 75 | 8 | 2 | | DN Wyatt | England Women v India Women | Wankhede Stadium, Mumbai | 2023/24 |
| 42 | 67* | 9 | 1 | | NR Sciver | England Women v South Africa Women | Willowmoore Park Main Oval, Benoni | 2024/25 |
| 48 | 59 | 6 | 4 | | SIR Dunkley | England Women v Australia Women | Sydney Cricket Ground, Sydney | 2024/25 |
| 40 | 55* | 10 | 0 | | NR Sciver | England Women v West Indies Women | The 1st Central County Ground, Hove | 2025 |
| 40 | 66 | 10 | 0 | | NR Sciver | England Women v India Women | Trent Bridge, Nottingham | 2025 |
| 46 | 66 | 7 | 3 | | DN Wyatt | England Women v India Women | The Kia Oval, Kennington | 2025 |
