| Runs |
Wkts |
| 428 | 18 | Middlesex v Gloucestershire | Brunton Memorial Ground, Radlett | 2022 |
| 427 | 14 | Gloucestershire v Somerset | County Ground, Bristol | 2006 |
| 421 | 12 | Sussex v Gloucestershire | The PROBIZ County Ground, Hove | 2012 |
| 414 | 10 | Gloucestershire v Middlesex | Brightside Ground, Bristol | 2018 |
| 412 | 10 | Gloucestershire v Kent | Seat Unique Stadium, Bristol | 2025 |
| 403 | 11 | Middlesex v Gloucestershire | Uxbridge Cricket Club Ground, Uxbridge | 2011 |
| 400 | 15 | Glamorgan v Gloucestershire | Sophia Gardens, Cardiff | 2018 |
| 399 | 12 | Somerset v Gloucestershire | County Ground, Taunton | 2010 |
| 399 | 12 | Gloucestershire v Middlesex | Seat Unique Stadium, Bristol | 2025 |
| 398 | 20 | Gloucestershire v Kent | Archdeacon Meadow, Gloucester | 2010 |
| 398 | 10 | Gloucestershire v Glamorgan | County Ground, Bristol | 2021 |
| 395 | 9 | Gloucestershire v Northamptonshire | College Ground, Cheltenham | 2013 |
| 395 | 14 | Somerset v Gloucestershire | The Cooper Associates County Ground, Taunton | 2020 |
| 394 | 10 | Gloucestershire v Essex | College Ground, Cheltenham | 2016 |
| 391 | 14 | Essex v Gloucestershire | The Cloud County Ground, Chelmsford | 2023 |
| 390 | 11 | Somerset v Gloucestershire | The Cooper Associates County Ground, Taunton | 2024 |
| 389 | 14 | Gloucestershire v Glamorgan | County Ground, Bristol | 2003 |
| 387 | 8 | Gloucestershire v Essex | County Ground, Bristol | 2019 |
| 385 | 14 | Middlesex v Gloucestershire | Old Deer Park, Richmond | 2015 |
| 385 | 9 | Kent v Gloucestershire | Spitfire Ground, St Lawrence, Canterbury | 2022 |
| 383 | 13 | Somerset v Gloucestershire | County Ground, Taunton | 2006 |
| 382 | 14 | Worcestershire v Gloucestershire | County Ground, New Road, Worcester | 2006 |
| 382 | 15 | Hampshire v Gloucestershire | The Rose Bowl, Southampton | 2010 |
| 382 | 12 | Somerset v Gloucestershire | County Ground, Taunton | 2013 |
| 382 | 10 | Somerset v Gloucestershire | The Cooper Associates County Ground, Taunton | 2018 |
| 382 | 14 | Gloucestershire v Somerset | Seat Unique Stadium, Bristol | 2023 |
| 381 | 10 | Glamorgan v Gloucestershire | Sophia Gardens, Cardiff | 2006 |
| 379 | 12 | Worcestershire v Gloucestershire | County Ground, New Road, Worcester | 2012 |
| 378 | 9 | Gloucestershire v Somerset | Seat Unique Stadium, Bristol | 2024 |
| 374 | 16 | Sussex v Gloucestershire | The Brighton and Hove Jobs County Ground, Hove | 2014 |
| 374 | 11 | Gloucestershire v Sussex | College Ground, Cheltenham | 2025 |
