| Inns | HS |
| 216-8 | 38 | Lancashire v Durham | Seat Unique Riverside Ground, Chester-le-Street | 2024 |
| 201-4 | 49 | Lancashire v Hampshire | The Ageas Bowl, Southampton | 2013 |
| 201-9 | 45 | Lancashire v Northamptonshire | Emirates Old Trafford, Manchester | 2024 |
| 184-9 | 42 | Lancashire v Somerset | The Cooper Associates County Ground, Taunton | 2021 |
| 183-6 | 44 | Lancashire v Essex | The Ford County Ground, Chelmsford | 2010 |
| 183-5 | 47 | Lancashire v Derbyshire | The Incora County Ground, Derby | 2022 |
| 180-4 | 42 | Lancashire v Leicestershire | Grace Road, Leicester | 2010 |
| 180-8 | 39 | Lancashire v Yorkshire | Headingley, Leeds | 2023 |
| 179-7 | 39 | Lancashire v Derbyshire | Emirates Old Trafford, Manchester | 2024 |
| 178-6 | 44 | Lancashire v Derbyshire | Emirates Old Trafford, Manchester | 2025 |
| 176-3 | 43* | Lancashire v Durham | Emirates Riverside, Chester-le-Street | 2016 |
| 176-9 | 44 | Lancashire v Derbyshire | The 3aaa County Ground, Derby | 2017 |
| 173-5 | 40 | Lancashire v Derbyshire | Old Trafford, Manchester | 2006 |
| 173-9 | 48 | Lancashire v Leicestershire | Aigburth, Liverpool | 2017 |
| 170-6 | 43 | Lancashire v Yorkshire | Emerald Headingley Cricket Stadium, Leeds | 2019 |
| 169-8 | 42 | Lancashire v Warwickshire | Emirates Old Trafford, Manchester | 2022 |
| 168-6 | 46 | Lancashire v Derbyshire | County Ground, Derby | 2012 |
| 167 | 44 | Lancashire v Leicestershire | Old Trafford, Manchester | 2008 |
| 167 | 38 | Lancashire v Yorkshire | Headingley, Leeds | 2011 |
| 167-5 | 37 | Lancashire v Nottinghamshire | Trent Bridge, Nottingham | 2020 |
| 167 | 35 | Lancashire v Warwickshire | Edgbaston, Birmingham | 2025 |
| 166-7 | 47 | Lancashire v Northamptonshire | Edgbaston, Birmingham | 2015 |
| 166-7 | 41 | Lancashire v Nottinghamshire | Trent Bridge, Nottingham | 2021 |
| 166-8 | 46 | Lancashire v Yorkshire | Headingley, Leeds | 2024 |
| 165-7 | 41 | Lancashire v Derbyshire | Old Trafford, Manchester | 2009 |
| 164-8 | 44 | Lancashire v Derbyshire | Old Trafford, Manchester | 2005 |
| 164-8 | 44 | Lancashire v Durham | Emirates Old Trafford, Manchester | 2014 |
| 163-7 | 33 | Lancashire v Nottinghamshire | Trent Bridge, Nottingham | 2007 |
| 163-5 | 42 | Lancashire v Worcestershire | Emirates Old Trafford, Manchester | 2015 |
| 162-5 | 48 | Lancashire v Leicestershire | Old Trafford, Manchester | 2011 |
| 162 | 35 | Lancashire v Leicestershire | Uptonsteel County Ground, Leicester | 2024 |
| 159-6 | 41* | Lancashire v Northamptonshire | County Ground, Northampton | 2010 |
| 159-6 | 49* | Lancashire v Worcestershire | Emirates Old Trafford, Manchester | 2021 |
| 159 | 44 | Lancashire v Somerset | Edgbaston, Birmingham | 2025 |
| 157-7 | 45 | Lancashire v Leicestershire | Grace Road, Leicester | 2008 |
| 157-8 | 44 | Lancashire v Derbyshire | Emirates Old Trafford, Manchester | 2018 |
| 156-6 | 38 | Lancashire v Derbyshire | Old Trafford, Manchester | 2010 |
| 156-9 | 32 | Lancashire v Northamptonshire | Emirates Old Trafford, Manchester | 2025 |
| 156-7 | 42 | Lancashire v Durham | Emirates Old Trafford, Manchester | 2025 |
| 155-5 | 42* | Lancashire v Derbyshire | Emirates Old Trafford, Manchester | 2017 |
| 155-8 | 42 | Lancashire v Northamptonshire | Emirates Old Trafford, Manchester | 2022 |
| 154-7 | 28 | Lancashire v Worcestershire | Old Trafford, Manchester | 2011 |
| 153-7 | 38 | Lancashire v Northamptonshire | County Ground, Northampton | 2022 |
| 152-8 | 49* | Lancashire v Sussex | The PROBIZ County Ground, Hove | 2011 |
| 152-5 | 42* | Lancashire v Yorkshire | Headingley, Leeds | 2013 |
| 152-9 | 34 | Lancashire v Durham | Seat Unique Riverside Ground, Chester-le-Street | 2023 |
| 151-6 | 31 | Lancashire v Nottinghamshire | Old Trafford, Manchester | 2009 |
| 151-7 | 41 | Lancashire v Leicestershire | Grace Road, Leicester | 2014 |
| 151-8 | 36 | Lancashire v Hampshire | Edgbaston, Birmingham | 2022 |
| 150-6 | 43 | Lancashire v Yorkshire | Headingley, Leeds | 2008 |
