| Runs |
Out of |
4s |
6s |
| 60 | 85* | 12 | 2 | | HK Matthews | Melbourne Renegades Women v Adelaide Strikers Women | Karen Rolton Oval, Adelaide | 2024/25 |
| 54 | 81 | 12 | 1 | | JE Cameron | Melbourne Renegades Women v Sydney Thunder Women | North Sydney Oval, Sydney | 2017/18 |
| 56 | 87 | 11 | 2 | | DN Wyatt | Melbourne Renegades Women v Brisbane Heat Women | Allan Border Field, Brisbane | 2019/20 |
| 60 | 79 | 9 | 4 | | L Lee | Melbourne Renegades Women v Sydney Sixers Women | North Sydney Oval, Sydney | 2020/21 |
| 56 | 81* | 11 | 2 | | H Kaur | Melbourne Renegades Women v Sydney Thunder Women | Great Barrier Reef Arena, Mackay | 2021/22 |
| 48 | 78* | 12 | 0 | | SG Molineux | Melbourne Renegades Women v Melbourne Stars Women | Melbourne Cricket Ground, Melbourne | 2018/19 |
| 56 | 75 | 8 | 4 | | JE Cameron | Melbourne Renegades Women v Hobart Hurricanes Women | St Kilda Cricket Ground, Melbourne | 2019/20 |
| 54 | 64 | 9 | 3 | | SG Molineux | Melbourne Renegades Women v Adelaide Strikers Women | St Kilda Cricket Ground, Melbourne | 2024/25 |
| 50 | 62 | 8 | 3 | | SG Molineux | Melbourne Renegades Women v Perth Scorchers Women | Camberwell Sports Ground, Melbourne | 2017/18 |
| 44 | 74* | 11 | 0 | | DN Wyatt | Melbourne Renegades Women v Perth Scorchers Women | Western Australia Cricket Association West Ground, Perth | 2019/20 |
| 48 | 76* | 9 | 2 | | JE Cameron | Melbourne Renegades Women v Melbourne Stars Women | St Kilda Cricket Ground, Melbourne | 2019/20 |
| 40 | 53* | 10 | 0 | | SG Molineux | Melbourne Renegades Women v Hobart Hurricanes Women | Blundstone Arena, Hobart | 2017/18 |
| 40 | 61 | 10 | 0 | | DN Wyatt | Melbourne Renegades Women v Adelaide Strikers Women | Karen Rolton Oval, Adelaide | 2019/20 |
| 44 | 73 | 8 | 2 | | AJ Lanning | Melbourne Renegades Women v Melbourne Stars Women | Eastern Oval, Ballarat | 2019/20 |
| 52 | 65 | 4 | 6 | | H Kaur | Melbourne Renegades Women v Brisbane Heat Women | Karen Rolton Oval, Adelaide | 2021/22 |
| 40 | 52 | 10 | 0 | | JI Rodrigues | Melbourne Renegades Women v Brisbane Heat Women | Karen Rolton Oval, Adelaide | 2021/22 |
| 44 | 75* | 8 | 2 | | AMC Jayangani | Melbourne Renegades Women v Hobart Hurricanes Women | Blundstone Arena, Hobart | 2022/23 |
| 42 | 61 | 9 | 1 | | CA Webb | Melbourne Renegades Women v Perth Scorchers Women | St Kilda Cricket Ground, Melbourne | 2024/25 |
| 36 | 65 | 9 | 0 | | AE Satterthwaite | Melbourne Renegades Women v Hobart Hurricanes Women | Blundstone Arena, Hobart | 2017/18 |
| 38 | 62 | 8 | 1 | | DN Wyatt | Melbourne Renegades Women v Adelaide Strikers Women | St Kilda Cricket Ground, Melbourne | 2018/19 |
| 38 | 57 | 8 | 1 | | DN Wyatt | Melbourne Renegades Women v Sydney Sixers Women | Drummoyne Oval, Sydney | 2019/20 |
| 44 | 54* | 5 | 4 | | GL Wareham | Melbourne Renegades Women v Sydney Sixers Women | Sydney Showground Stadium, Sydney | 2020/21 |
| 36 | 75* | 9 | 0 | | JI Rodrigues | Melbourne Renegades Women v Sydney Thunder Women | University of Tasmania Stadium, Launceston | 2021/22 |
| 36 | 62 | 9 | 0 | | E Jones | Melbourne Renegades Women v Brisbane Heat Women | Karen Rolton Oval, Adelaide | 2021/22 |
| 40 | 43 | 7 | 2 | | TT Beaumont | Melbourne Renegades Women v Sydney Sixers Women | St Kilda Cricket Ground, Melbourne | 2023/24 |
| 42 | 69 | 6 | 3 | | GL Wareham | Melbourne Renegades Women v Hobart Hurricanes Women | Ninja Stadium, Hobart | 2024/25 |
| 40 | 60* | 7 | 2 | | HK Matthews | Melbourne Renegades Women v Sydney Thunder Women | St Kilda Cricket Ground, Melbourne | 2024/25 |
| 32 | 47 | 8 | 0 | | RH Priest | Melbourne Renegades Women v Sydney Thunder Women | Allan Border Field, Brisbane | 2015/16 |
| 32 | 59 | 8 | 0 | | DN Wyatt | Melbourne Renegades Women v Sydney Thunder Women | Spotless Stadium, Sydney | 2018/19 |
| 36 | 69 | 6 | 2 | | JE Cameron | Melbourne Renegades Women v Sydney Thunder Women | Blacktown Olympic Park Oval, Sydney | 2019/20 |
| 34 | 50* | 7 | 1 | | JE Cameron | Melbourne Renegades Women v Brisbane Heat Women | Allan Border Field, Brisbane | 2019/20 |
| 36 | 48 | 6 | 2 | | L Lee | Melbourne Renegades Women v Adelaide Strikers Women | Sydney Showground Stadium, Sydney | 2020/21 |
| 42 | 73* | 3 | 5 | | H Kaur | Melbourne Renegades Women v Adelaide Strikers Women | Lilac Hill Park, Perth | 2021/22 |
| 32 | 55* | 8 | 0 | | SG Molineux | Melbourne Renegades Women v Sydney Thunder Women | Blundstone Arena, Hobart | 2022/23 |
| 38 | 54 | 5 | 3 | | JE Cameron | Melbourne Renegades Women v Adelaide Strikers Women | Karen Rolton Oval, Adelaide | 2023/24 |
| 34 | 46 | 7 | 1 | | HK Matthews | Melbourne Renegades Women v Brisbane Heat Women | Allan Border Field, Brisbane | 2023/24 |
| 32 | 40* | 8 | 0 | | E de Broughe | Melbourne Renegades Women v Hobart Hurricanes Women | Blundstone Arena, Hobart | 2023/24 |
| 40 | 61 | 4 | 4 | | GL Wareham | Melbourne Renegades Women v Sydney Sixers Women | Adelaide Oval, Adelaide | 2024/25 |
| 34 | 41 | 7 | 1 | | HK Matthews | Melbourne Renegades Women v Perth Scorchers Women | St Kilda Cricket Ground, Melbourne | 2024/25 |
| 34 | 46* | 7 | 1 | | DJS Dottin | Melbourne Renegades Women v Adelaide Strikers Women | Karen Rolton Oval, Adelaide | 2024/25 |
| 34 | 66* | 7 | 1 | | NM Faltum | Melbourne Renegades Women v Melbourne Stars Women | Melbourne Cricket Ground, Melbourne | 2024/25 |
| 34 | 42* | 7 | 1 | | SG Molineux | Melbourne Renegades Women v Sydney Thunder Women | St Kilda Cricket Ground, Melbourne | 2024/25 |
| 32 | 69 | 8 | 0 | | HK Matthews | Melbourne Renegades Women v Brisbane Heat Women | Melbourne Cricket Ground, Melbourne | 2024/25 |
