| Runs |
Wkts |
| 399 | 14 | Brisbane Heat Women v Melbourne Renegades Women | Karen Rolton Oval, Adelaide | 2021/22 |
| 389 | 12 | Melbourne Renegades Women v Sydney Thunder Women | North Sydney Oval, Sydney | 2017/18 |
| 371 | 9 | Adelaide Strikers Women v Melbourne Renegades Women | Karen Rolton Oval, Adelaide | 2024/25 |
| 368 | 8 | Brisbane Heat Women v Melbourne Renegades Women | Allan Border Field, Brisbane | 2019/20 |
| 368 | 17 | Melbourne Renegades Women v Brisbane Heat Women | St Kilda Cricket Ground, Melbourne | 2023/24 |
| 357 | 15 | Melbourne Renegades Women v Sydney Sixers Women | Adelaide Oval, Adelaide | 2024/25 |
| 348 | 8 | Perth Scorchers Women v Melbourne Renegades Women | Western Australia Cricket Association Ground, Perth | 2021/22 |
| 346 | 6 | Melbourne Renegades Women v Sydney Thunder Women | Great Barrier Reef Arena, Mackay | 2021/22 |
| 343 | 12 | Melbourne Renegades Women v Sydney Thunder Women | St Kilda Cricket Ground, Melbourne | 2023/24 |
| 343 | 10 | Perth Scorchers Women v Melbourne Renegades Women | Western Australia Cricket Association Ground, Perth | 2023/24 |
| 339 | 7 | Brisbane Heat Women v Melbourne Renegades Women | Great Barrier Reef Arena, Mackay | 2022/23 |
| 339 | 12 | Melbourne Renegades Women v Sydney Sixers Women | Eastern Oval, Ballarat | 2022/23 |
| 336 | 16 | Brisbane Heat Women v Melbourne Renegades Women | Allan Border Field, Brisbane | 2023/24 |
| 335 | 8 | Sydney Sixers Women v Melbourne Renegades Women | North Sydney Oval, Sydney | 2020/21 |
| 334 | 6 | Melbourne Renegades Women v Melbourne Stars Women | Eastern Oval, Ballarat | 2019/20 |
| 331 | 13 | Hobart Hurricanes Women v Melbourne Renegades Women | Blundstone Arena, Hobart | 2023/24 |
| 331 | 14 | Melbourne Renegades Women v Melbourne Stars Women | Melbourne Cricket Ground, Melbourne | 2024/25 |
| 330 | 15 | Melbourne Renegades Women v Melbourne Stars Women | Sydney Showground Stadium, Sydney | 2020/21 |
| 329 | 8 | Perth Scorchers Women v Melbourne Renegades Women | Western Australia Cricket Association West Ground, Perth | 2018/19 |
| 329 | 10 | Brisbane Heat Women v Melbourne Renegades Women | Allan Border Field, Brisbane | 2019/20 |
| 327 | 15 | Melbourne Renegades Women v Brisbane Heat Women | Geelong Cricket Ground, Geelong | 2018/19 |
| 325 | 8 | Melbourne Renegades Women v Melbourne Stars Women | St Kilda Cricket Ground, Melbourne | 2019/20 |
| 322 | 9 | Adelaide Strikers Women v Melbourne Renegades Women | Lilac Hill Park, Perth | 2021/22 |
| 322 | 16 | Melbourne Renegades Women v Sydney Sixers Women | St Kilda Cricket Ground, Melbourne | 2023/24 |
| 315 | 13 | Melbourne Renegades Women v Adelaide Strikers Women | St Kilda Cricket Ground, Melbourne | 2024/25 |
| 311 | 14 | Adelaide Strikers Women v Melbourne Renegades Women | Gliderol Stadium, Adelaide | 2017/18 |
| 310 | 17 | Brisbane Heat Women v Melbourne Renegades Women | Allan Border Field, Brisbane | 2024/25 |
| 307 | 11 | Melbourne Renegades Women v Adelaide Strikers Women | St Kilda Cricket Ground, Melbourne | 2018/19 |
| 306 | 10 | Adelaide Strikers Women v Melbourne Renegades Women | Karen Rolton Oval, Adelaide | 2019/20 |
| 303 | 13 | Melbourne Renegades Women v Sydney Sixers Women | St Kilda Cricket Ground, Melbourne | 2015/16 |
