| Runs |
Out of |
4s |
6s |
| 84 | 122 | 15 | 4 | | Babar Azam | Pakistan v South Africa | SuperSport Park, Centurion | 2020/21 |
| 82 | 105* | 10 | 7 | | Hasan Nawaz | Pakistan v New Zealand | Eden Park, Auckland | 2024/25 |
| 74 | 110* | 11 | 5 | | Babar Azam | Pakistan v England | National Bank Cricket Arena, Karachi | 2022/23 |
| 74 | 98* | 11 | 5 | | Saim Ayub | Pakistan v South Africa | SuperSport Park, Centurion | 2024/25 |
| 70 | 111* | 10 | 5 | | Ahmed Shehzad | Pakistan v Bangladesh | Shere Bangla National Stadium, Mirpur | 2013/14 |
| 66 | 83 | 12 | 3 | | Mukhtar Ahmed | Pakistan v Zimbabwe | Gaddafi Stadium, Lahore | 2015 |
| 66 | 91 | 12 | 3 | | Fakhar Zaman | Pakistan v Australia | Harare Sports Club, Harare | 2018 |
| 70 | 99* | 10 | 5 | | Mohammad Hafeez | Pakistan v New Zealand | Seddon Park, Hamilton | 2020/21 |
| 74 | 107* | 8 | 7 | | Mohammad Haris | Pakistan v Bangladesh | Gaddafi Stadium, Lahore | 2025 |
| 58 | 97* | 13 | 1 | | Babar Azam | Pakistan v West Indies | National Stadium, Karachi | 2017/18 |
| 58 | 90 | 13 | 1 | | Babar Azam | Pakistan v South Africa | Bidvest Wanderers Stadium, Johannesburg | 2018/19 |
| 62 | 101* | 11 | 3 | | Babar Azam | Pakistan v New Zealand | Gaddafi Stadium, Lahore | 2023 |
| 60 | 86 | 9 | 4 | | Mohammad Hafeez | Pakistan v South Africa | SuperSport Park, Centurion | 2012/13 |
| 60 | 94 | 9 | 4 | | Umar Akmal | Pakistan v Australia | Shere Bangla National Stadium, Mirpur | 2013/14 |
| 58 | 89* | 10 | 3 | | Sarfraz Ahmed | Pakistan v Scotland | Raeburn Place, Edinburgh | 2018 |
| 58 | 89 | 10 | 3 | | Mohammad Rizwan | Pakistan v New Zealand | McLean Park, Napier | 2020/21 |
| 66 | 104* | 6 | 7 | | Mohammad Rizwan | Pakistan v South Africa | Gaddafi Stadium, Lahore | 2020/21 |
| 58 | 87 | 10 | 3 | | Mohammad Rizwan | Pakistan v West Indies | National Stadium, Karachi | 2021/22 |
| 54 | 72 | 9 | 3 | | Imran Nazir | Pakistan v Bangladesh | Pallekele Cricket Stadium, Pallekele | 2012/13 |
| 60 | 98* | 6 | 6 | | Ahmed Shehzad | Pakistan v Zimbabwe | Harare Sports Club, Harare | 2013 |
| 52 | 86 | 10 | 2 | | Babar Azam | Pakistan v World XI | Gaddafi Stadium, Lahore | 2017/18 |
| 54 | 73 | 9 | 3 | | Fakhar Zaman | Pakistan v Australia | Harare Sports Club, Harare | 2018 |
| 56 | 79* | 8 | 4 | | Mohammad Rizwan | Pakistan v Namibia | Sheikh Zayed Stadium, Abu Dhabi | 2021/22 |
| 60 | 78 | 6 | 6 | | Fakhar Zaman | Pakistan v Ireland | Castle Avenue, Dublin | 2024 |
| 50 | 89 | 8 | 3 | | Ahmed Shehzad | Pakistan v World XI | Gaddafi Stadium, Lahore | 2017/18 |
| 48 | 74* | 9 | 2 | | Mohammad Rizwan | Pakistan v South Africa | Imperial Wanderers Stadium, Johannesburg | 2020/21 |
| 46 | 82* | 10 | 1 | | Mohammad Rizwan | Pakistan v Zimbabwe | Harare Sports Club, Harare | 2020/21 |
| 50 | 85 | 8 | 3 | | Babar Azam | Pakistan v England | Trent Bridge, Nottingham | 2021 |
| 48 | 79 | 9 | 2 | | Babar Azam | Pakistan v West Indies | National Stadium, Karachi | 2021/22 |
| 44 | 79* | 11 | 0 | | Babar Azam | Pakistan v New Zealand | Hagley Oval, Christchurch | 2022/23 |
| 52 | 98* | 7 | 4 | | Mohammad Rizwan | Pakistan v New Zealand | Rawalpindi Cricket Stadium, Rawalpindi | 2023 |
| 54 | 75 | 6 | 5 | | Babar Azam | Pakistan v Ireland | Castle Avenue, Dublin | 2024 |
| 54 | 63 | 6 | 5 | | Sahibzada Farhan | Pakistan v Bangladesh | Shere Bangla National Stadium, Mirpur | 2025 |
