| 115 | Fakhar Zaman | for Lahore Qalandars | Rawalpindi Cricket Stadium, Rawalpindi | 2022/23 | tt12052 |
| 111* | Babar Azam | for Peshawar Zalmi | Gaddafi Stadium, Lahore | 2023/24 | tt13277 |
| 105 | Sharjeel Khan | for Karachi Kings | National Stadium, Karachi | 2020/21 | tt9405 |
| 104 | RR Rossouw | for Quetta Gladiators | Rawalpindi Cricket Stadium, Rawalpindi | 2024/25 | tt15097 |
| 102* | HC Brook | for Lahore Qalandars | Gaddafi Stadium, Lahore | 2021/22 | tt10605 |
| 100* | Usman Khan | for Multan Sultans | Rawalpindi Cricket Stadium, Rawalpindi | 2023/24 | tt13346 |
| 100* | Hasan Nawaz | for Quetta Gladiators | Rawalpindi Cricket Stadium, Rawalpindi | 2024/25 | tt15097 |
| 98* | Mohammad Hafeez | for Lahore Qalandars | Gaddafi Stadium, Lahore | 2019/20 | tt8804 |
| 92* | Imad Wasim | for Karachi Kings | Rawalpindi Cricket Stadium, Rawalpindi | 2022/23 | tt12038 |
| 88 | Kamran Akmal | for Peshawar Zalmi | Dubai Sports City Stadium, Dubai | 2016/17 | tt6183 |
| 87 | Aamer Jamal | for Peshawar Zalmi | Rawalpindi Cricket Stadium, Rawalpindi | 2023/24 | tt13297 |
| 87 | Mohammad Haris | for Peshawar Zalmi | Rawalpindi Cricket Stadium, Rawalpindi | 2024/25 | tt15013 |
| 86* | LJ Wright | for Quetta Gladiators | Dubai Sports City Stadium, Dubai | 2015/16 | tt5544 |
| 81* | SR Watson | for Quetta Gladiators | Dubai Sports City Stadium, Dubai | 2018/19 | tt7549 |
| 81 | Babar Azam | for Karachi Kings | Sheikh Zayed Stadium, Abu Dhabi | 2021 | tt9667 |
| 80* | Tamim Iqbal | for Peshawar Zalmi | Sharjah Cricket Association Stadium, Sharjah | 2015/16 | tt5574 |
| 79 | Mohammad Haris | for Peshawar Zalmi | Rawalpindi Cricket Stadium, Rawalpindi | 2022/23 | tt12060 |
| 75 | Sohail Akhtar | for Lahore Qalandars | National Stadium, Karachi | 2018/19 | tt7764 |
| 75* | Babar Azam | for Peshawar Zalmi | National Bank Cricket Arena, Karachi | 2022/23 | tt12009 |
| 75 | Shan Masood | for Multan Sultans | Rawalpindi Cricket Stadium, Rawalpindi | 2022/23 | tt12045 |
