| 145* | JJ Roy | for Quetta Gladiators | Rawalpindi Cricket Stadium, Rawalpindi | 2022/23 | tt12048 |
| 121 | RR Rossouw | for Multan Sultans | Rawalpindi Cricket Stadium, Rawalpindi | 2022/23 | tt12053 |
| 117 | Sharjeel Khan | for Islamabad United | Dubai Sports City Stadium, Dubai | 2015/16 | tt5599 |
| 106 | Sahibzada Farhan | for Islamabad United | Rawalpindi Cricket Stadium, Rawalpindi | 2024/25 | tt15012 |
| 105* | Usman Khawaja | for Islamabad United | Sheikh Zayed Stadium, Abu Dhabi | 2021 | tt9694 |
| 104* | HE van der Dussen | for Lahore Qalandars | Gaddafi Stadium, Lahore | 2023/24 | tt13274 |
| 99 | WCF Smeed | for Quetta Gladiators | Gaddafi Stadium, Lahore | 2021/22 | tt10585 |
| 97 | WCF Smeed | for Quetta Gladiators | National Stadium, Karachi | 2021/22 | tt10519 |
| 96 | Fakhar Zaman | for Lahore Qalandars | Gaddafi Stadium, Lahore | 2022/23 | tt12024 |
| 91* | SR Watson | for Quetta Gladiators | Sheikh Zayed Stadium, Abu Dhabi | 2018/19 | tt7750 |
| 90* | Babar Azam | for Karachi Kings | National Stadium, Karachi | 2021/22 | tt10539 |
| 86 | DA Warner | for Karachi Kings | Rawalpindi Cricket Stadium, Rawalpindi | 2024/25 | tt15111 |
| 85* | Sohaib Maqsood | for Multan Sultans | Dubai Sports City Stadium, Dubai | 2017/18 | tt6886 |
| 85 | Azam Khan | for Islamabad United | Gaddafi Stadium, Lahore | 2021/22 | tt10591 |
| 84 | JM Vince | for Multan Sultans | National Stadium, Karachi | 2020/21 | tt9402 |
| 82* | Mohammad Rizwan | for Multan Sultans | Sheikh Zayed Stadium, Abu Dhabi | 2021 | tt9654 |
| 82* | AD Hales | for Islamabad United | National Stadium, Karachi | 2021/22 | tt10526 |
| 82 | Mohammad Rizwan | for Multan Sultans | National Stadium, Karachi | 2021/22 | tt10541 |
| 81 | Sarfraz Ahmed | for Quetta Gladiators | National Stadium, Karachi | 2020/21 | tt9411 |
| 80* | Imad Wasim | for Karachi Kings | National Bank Cricket Arena, Karachi | 2022/23 | tt11984 |
| 80 | Shadab Khan | for Islamabad United | Rawalpindi Cricket Stadium, Rawalpindi | 2023/24 | tt13297 |
| 79* | JL Denly | for Karachi Kings | Gaddafi Stadium, Lahore | 2017/18 | tt6912 |
| 78 | CS Delport | for Lahore Qalandars | Sharjah Cricket Association Stadium, Sharjah | 2015/16 | tt5578 |
| 78 | Babar Azam | for Karachi Kings | National Stadium, Karachi | 2019/20 | tt8796 |
| 77 | Shadab Khan | for Islamabad United | Rawalpindi Cricket Stadium, Rawalpindi | 2019/20 | tt8849 |
| 77* | Babar Azam | for Karachi Kings | National Stadium, Karachi | 2020/21 | tt9421 |
| 75* | Umar Akmal | for Quetta Gladiators | Dubai Sports City Stadium, Dubai | 2018/19 | tt7530 |
| 75 | RR Rossouw | for Multan Sultans | Multan Cricket Stadium, Multan | 2022/23 | tt11989 |
| 75 | Abdullah Shafiq | for Lahore Qalandars | Gaddafi Stadium, Lahore | 2022/23 | tt12024 |
| 75 | JJ Roy | for Quetta Gladiators | Gaddafi Stadium, Lahore | 2023/24 | tt13253 |
| 75 | Azam Khan | for Islamabad United | Gaddafi Stadium, Lahore | 2023/24 | tt13277 |
