| Runs |
Wkts |
| 872 | 13 | South Africa v Australia | Liberty Life Wanderers Stadium, Johannesburg | 2005/06 |
| 754 | 15 | South Africa v Sri Lanka | Feroz Shah Kotla, Delhi | 2023/24 |
| 743 | 12 | South Africa v Australia | Sahara Stadium Kingsmead, Durban | 2016/17 |
| 730 | 9 | South Africa v West Indies | Bidvest Wanderers Stadium, Johannesburg | 2014/15 |
| 707 | 9 | Pakistan v South Africa | National Bank Cricket Arena, Karachi | 2024/25 |
| 694 | 15 | South Africa v Sri Lanka | PPC Newlands, Cape Town | 2016/17 |
| 689 | 12 | South Africa v England | Mangaung Oval, Bloemfontein | 2022/23 |
| 680 | 14 | South Africa v Sri Lanka | SuperSport Park, Centurion | 2016/17 |
| 674 | 15 | New Zealand v South Africa | Gaddafi Stadium, Lahore | 2024/25 |
| 671 | 16 | Australia v South Africa | Warner Park, Basseterre | 2006/07 |
| 668 | 14 | South Africa v Australia | SuperSport Park, Centurion | 2023/24 |
| 665 | 9 | South Africa v Zimbabwe | Sedgars Park, Potchefstroom | 2006/07 |
| 665 | 15 | South Africa v Pakistan | Imperial Wanderers Stadium, Johannesburg | 2020/21 |
| 662 | 14 | India v South Africa | Wankhede Stadium, Mumbai | 2015/16 |
| 661 | 18 | South Africa v Australia | Mangaung Oval, Bloemfontein | 2023/24 |
| 658 | 11 | England v South Africa | The Ageas Bowl, Southampton | 2017 |
| 656 | 10 | South Africa v Australia | St George's Park, Port Elizabeth | 2001/02 |
| 655 | 10 | Australia v South Africa | Harare Sports Club, Harare | 2014 |
| 652 | 15 | South Africa v Pakistan | Bidvest Wanderers Stadium, Johannesburg | 2012/13 |
| 649 | 13 | India v South Africa | Captain Roop Singh Stadium, Gwalior | 2009/10 |
| 649 | 14 | South Africa v England | Mangaung Oval, Bloemfontein | 2015/16 |
| 648 | 17 | Sri Lanka v South Africa | Pallekele Cricket Stadium, Pallekele | 2018 |
| 645 | 13 | West Indies v South Africa | Queen's Park (New), St George's | 2006/07 |
| 640 | 12 | India v South Africa | Sardar Patel Stadium, Motera, Ahmedabad | 2009/10 |
| 640 | 16 | Australia v South Africa | Emirates Old Trafford, Manchester | 2019 |
| 639 | 14 | Bangladesh v South Africa | The Kia Oval, Kennington | 2019 |
| 638 | 12 | South Africa v Zimbabwe | OUTsurance Oval, Bloemfontein | 2010/11 |
| 637 | 11 | South Africa v England | SuperSport Park, Centurion | 2015/16 |
| 636 | 17 | India v South Africa | The SWALEC Stadium, Cardiff | 2013 |
| 633 | 17 | South Africa v England | De Beers Diamond Oval, Kimberley | 2022/23 |
| 631 | 12 | Australia v South Africa | Sydney Cricket Ground, Sydney | 2005/06 |
| 630 | 17 | India v South Africa | Vidarbha Cricket Association Ground, Nagpur | 1999/00 |
| 626 | 12 | South Africa v Sri Lanka | Bidvest Wanderers Stadium, Johannesburg | 2011/12 |
| 624 | 17 | South Africa v England | SuperSport Park, Centurion | 2009/10 |
| 623 | 18 | South Africa v Australia | PPC Newlands, Cape Town | 2016/17 |
| 622 | 14 | Ireland v South Africa | The Village, Malahide, Dublin | 2021 |
| 622 | 18 | South Africa v West Indies | Buffalo Park, East London | 2022/23 |
| 621 | 14 | Ireland v South Africa | Manuka Oval, Canberra | 2014/15 |
| 620 | 16 | South Africa v Pakistan | SuperSport Park, Centurion | 2006/07 |
| 618 | 16 | Zimbabwe v South Africa | Harare Sports Club, Harare | 2007/08 |
| 616 | 14 | South Africa v Zimbabwe | Seddon Park, Hamilton | 2014/15 |
| 615 | 15 | South Africa v England | Mercedes Benz Park, East London | 2004/05 |
| 615 | 15 | Bangladesh v South Africa | Wankhede Stadium, Mumbai | 2023/24 |
| 614 | 8 | South Africa v West Indies | New Wanderers Stadium, Johannesburg | 2003/04 |
| 612 | 17 | South Africa v Pakistan | SuperSport Park, Centurion | 2020/21 |
| 612 | 10 | New Zealand v South Africa | Gaddafi Stadium, Lahore | 2024/25 |
| 607 | 9 | West Indies v South Africa | Windsor Park, Roseau | 2010 |
| 606 | 16 | England v South Africa | Headingley, Leeds | 2017 |
| 604 | 15 | England v South Africa | Seat Unique Riverside Ground, Chester-le-Street | 2022 |
| 603 | 10 | India v South Africa | Nehru Stadium, Kochi | 1999/00 |
| 603 | 12 | South Africa v Sri Lanka | De Beers Diamond Oval, Kimberley | 2011/12 |
| 602 | 16 | South Africa v Bangladesh | Eurolux Boland Park, Paarl | 2017/18 |
| 601 | 12 | India v South Africa | Modi Stadium, Kanpur | 2015/16 |
| 600 | 14 | Australia v South Africa | Blundstone Arena, Hobart | 2018/19 |
