| 193 | (150,43*) | M Kapp | South Africa Women v England Women | The Cooper Associates County Ground, Taunton | 2022 |
| 134 | (96*,38) | EMA Hurly | South Africa Women v England Women | St George's Park, Port Elizabeth | 1960/61 |
| 130 | (30,100) | BG Williams | South Africa Women v New Zealand Women | New Wanderers Stadium, Johannesburg | 1971/72 |
| 126 | (105*,21*) | Y van Mentz | South Africa Women v England Women | Newlands, Cape Town | 1960/61 |
| 119 | (102,17) | M du Preez | South Africa Women v India Women | Gangothri Glades Cricket Ground, Mysore | 2014/15 |
| 116 | (21,95) | AL Hodgkinson | South Africa Women v England Women | Denis Compton Oval, Shenley | 2003 |
| 108 | (83,25) | C van der Westhuizen | South Africa Women v England Women | Denis Compton Oval, Shenley | 2003 |
| 96 | (2,94) | CA Gildenhuys | South Africa Women v New Zealand Women | Newlands, Cape Town | 1971/72 |
| 93 | (25,68) | SM Charlton | South Africa Women v England Women | Kingsmead, Durban | 1960/61 |
| 91 | (56,35) | T Chetty | South Africa Women v India Women | Gangothri Glades Cricket Ground, Mysore | 2014/15 |
| 88 | (17,71) | SS Viljoen | South Africa Women v India Women | BOE Park, Paarl | 2001/02 |
| 86 | (24,62*) | SM Charlton | South Africa Women v England Women | St George's Park, Port Elizabeth | 1960/61 |
| 86 | (28,58) | B Lang | South Africa Women v England Women | Newlands, Cape Town | 1960/61 |
| 85 | (8,77) | AL Hodgkinson | South Africa Women v India Women | BOE Park, Paarl | 2001/02 |
| 83 | (72,11*) | BA Botha | South Africa Women v New Zealand Women | Newlands, Cape Town | 1971/72 |
| 83 | (83) | M Terblanche | South Africa Women v Netherlands Women | Hazelaarweg, Rotterdam | 2007 |
| 75 | (62,13) | CA Gildenhuys | South Africa Women v New Zealand Women | Kingsmead, Durban | 1971/72 |
| 74 | (74,0) | J Logtenberg | South Africa Women v England Women | Denis Compton Oval, Shenley | 2003 |
| 69 | (5,64) | CL Tryon | South Africa Women v Australia Women | Western Australia Cricket Association Ground, Perth | 2023/24 |
| 64 | (0,64) | D Tucker | South Africa Women v Australia Women | Western Australia Cricket Association Ground, Perth | 2023/24 |
| 63 | (12,51) | B Lang | South Africa Women v England Women | New Wanderers Stadium, Johannesburg | 1960/61 |
| 61 | (0,61) | C Brits | South Africa Women v England Women | County Ground, Taunton | 2003 |
| 60 | (21,39) | D Moe | South Africa Women v New Zealand Women | New Wanderers Stadium, Johannesburg | 1971/72 |
| 60 | (41,19) | M Terblanche | South Africa Women v England Women | County Ground, Taunton | 2003 |
| 56 | (30,26) | CS Terblanche | South Africa Women v Netherlands Women | Hazelaarweg, Rotterdam | 2007 |
| 55 | (34,21) | JA Gove | South Africa Women v England Women | Newlands, Cape Town | 1960/61 |
| 55 | (37,18) | SD van Zyl | South Africa Women v England Women | Denis Compton Oval, Shenley | 2003 |
| 54 | (3,51*) | JA Gove | South Africa Women v New Zealand Women | New Wanderers Stadium, Johannesburg | 1971/72 |
| 53 | (1,52*) | Y van der Merwe | South Africa Women v England Women | Denis Compton Oval, Shenley | 2003 |
| 51 | (29,22) | C van der Westhuizen | South Africa Women v England Women | County Ground, Taunton | 2003 |
| 51 | (0,51) | SM Benade | South Africa Women v Netherlands Women | Hazelaarweg, Rotterdam | 2007 |
