| 146 | LMP Simmons | for Trinidad and Tobago | Coolidge Cricket Ground, Coolidge | 2020/21 | a28251 |
| 133 | AS Athanaze | for Windward Islands | Queen's Park Oval, Port of Spain | 2022/23 | a29474 |
| 125* | XM Marshall | for Jamaica | Bourda, Georgetown | 2004/05 | a16207 |
| 123 | KAR Hodge | for Windward Islands | Queen's Park Oval, Port of Spain | 2019/20 | a27796 |
| 122* | NE Bonner | for Jamaica | Queen's Park Oval, Port of Spain | 2013/14 | a23246 |
| 119 | RRS Cornwall | for Leeward Islands | Coolidge Cricket Ground, Coolidge | 2017/18 | a25996 |
| 117* | JN Mohammed | for Trinidad and Tobago | Queen's Park Oval, Port of Spain | 2014/15 | a23989 |
| 114 | TA Hunte | for Barbados | Kensington Oval, Bridgetown | 1984/85 | a4300 |
| 110* | DS Smith | for Windward Islands | Arnos Vale Playing Field, Kingstown | 2012/13 | a22457 |
| 107 | T Theophile | for Windward Islands | Coolidge Cricket Ground, Coolidge | 2017/18 | a26185 |
| 105 | AM McCarthy | for Jamaica | Coolidge Cricket Ground, Coolidge | 2017/18 | a26051 |
| 105* | R Powell | for Jamaica | Sir Vivian Richards Stadium, North Sound | 2022/23 | a29583 |
| 104 | CAK Walton | for Jamaica | Coolidge Cricket Ground, Coolidge | 2017/18 | a26155 |
| 103* | HA Gomes | for Trinidad and Tobago | Queen's Park Oval, Port of Spain | 1977/78 | a2084 |
| 103 | RG Samuels | for Jamaica | Sabina Park, Kingston | 1993/94 | a8461 |
| 103* | DC Thomas | for Leeward Islands | Coolidge Cricket Ground, Coolidge | 2017/18 | a26138 |
| 102* | RK Currency | for Combined Campuses and Colleges | Guyana National Stadium, Providence | 2008/09 | a19219 |
| 101* | D Ganga | for Trinidad and Tobago | Albion Sports Complex, Albion | 2004/05 | a16194 |
| 101 | KC Brathwaite | for Barbados | Kensington Oval, Bridgetown | 2016/17 | a25091 |
| 100* | EN Trotman | for Barbados | Bourda, Georgetown | 1976/77 | a1838 |
| 100 | KLT Arthurton | for Leeward Islands | Kaiser Sports Club, Discovery Bay | 1997/98 | a10761 |
| 100 | LMP Simmons | for West Indies Under-19s | Antigua Recreation Ground, St John's | 2003/04 | a15368 |
| 100 | SM Jeffers | for Leeward Islands | Albion Sports Complex, Albion | 2006/07 | a17915 |
