| 177 | PR Stirling | Ireland v Canada | Armour Heights, Toronto | 2010 |
| 162 | PR Stirling | Ireland v United Arab Emirates | Bulawayo Athletic Club, Bulawayo | 2023 |
| 160* | EC Joyce | Ireland v Afghanistan | Civil Service Cricket Club, Stormont, Belfast | 2016 |
| 145* | A Balbirnie | Ireland v Afghanistan | Rajiv Gandhi International Cricket Stadium, Dehra Dun | 2018/19 |
| 142 | KJ O'Brien | Ireland v Kenya | Ruaraka Sports Club Ground, Nairobi | 2006/07 |
| 142 | PR Stirling | Ireland v England | The Ageas Bowl, Southampton | 2020 |
| 140 | HT Tector | Ireland v Bangladesh | The Cloud County Ground, Chelmsford | 2023 |
| 139 | WTS Porterfield | Ireland v United Arab Emirates | ICC Cricket Academy Ground, Dubai | 2017/18 |
| 138 | HT Tector | Ireland v Afghanistan | Sharjah Cricket Association Stadium, Sharjah | 2023/24 |
| 135 | A Balbirnie | Ireland v West Indies | The Village, Malahide, Dublin | 2019 |
| 131* | PR Stirling | Ireland v United Arab Emirates | Sheikh Zayed Stadium, Abu Dhabi | 2020/21 |
| 130 | PR Stirling | Ireland v Bangladesh | Castle Avenue, Dublin | 2019 |
| 128 | PR Stirling | Ireland v Afghanistan | Sheikh Zayed Stadium, Abu Dhabi | 2020/21 |
| 126 | PR Stirling | Ireland v United Arab Emirates | Old Hararians, Harare | 2017/18 |
| 121* | A Balbirnie | Ireland v Zimbabwe | Harare Sports Club, Harare | 2022/23 |
| 120 | PR Stirling | Ireland v New Zealand | The Village, Malahide, Dublin | 2022 |
| 120 | C Campher | Ireland v Scotland | Queens Sports Club, Bulawayo | 2023 |
| 119 | WTS Porterfield | Ireland v Afghanistan | Greater Noida Sports Complex Ground, Greater Noida | 2016/17 |
| 118 | PR Stirling | Ireland v Afghanistan | Sheikh Zayed Stadium, Abu Dhabi | 2020/21 |
| 116 | JP Bray | Ireland v Scotland | Gymkhana Club Ground, Nairobi | 2006/07 |
| 116* | EC Joyce | Ireland v Pakistan | Castle Avenue, Dublin | 2013 |
| 116* | EC Joyce | Ireland v United Arab Emirates | ICC Cricket Academy Ground, Dubai | 2017/18 |
| 115 | EJG Morgan | Ireland v Canada | Jaffery Sports Club Ground, Nairobi | 2006/07 |
| 115* | JP Bray | Ireland v Zimbabwe | Sabina Park, Kingston | 2006/07 |
| 113 | GC Wilson | Ireland v Netherlands | Castle Avenue, Dublin | 2010 |
| 113 | KJ O'Brien | Ireland v England | M Chinnaswamy Stadium, Bangalore | 2010/11 |
| 113 | PR Stirling | Ireland v Scotland | Raeburn Place, Edinburgh | 2011 |
| 113 | A Balbirnie | Ireland v England | The Ageas Bowl, Southampton | 2020 |
| 113 | HT Tector | Ireland v New Zealand | The Village, Malahide, Dublin | 2022 |
| 112* | WTS Porterfield | Ireland v Bermuda | Jaffery Sports Club Ground, Nairobi | 2006/07 |
| 112 | WTS Porterfield | Ireland v England | The Village, Malahide, Dublin | 2013 |
| 112 | EC Joyce | Ireland v Zimbabwe | Blundstone Arena, Hobart | 2014/15 |
| 111 | WTS Porterfield | Ireland v Papua New Guinea | Harare Sports Club, Harare | 2017/18 |
| 109 | PR Stirling | Ireland v Pakistan | Civil Service Cricket Club, Stormont, Belfast | 2011 |
| 109 | NJ O'Brien | Ireland v New Zealand | The Village, Malahide, Dublin | 2017 |
| 108 | WTS Porterfield | Ireland v Bangladesh | Civil Service Cricket Club, Stormont, Belfast | 2010 |
| 108 | HT Tector | Ireland v New Zealand | The Village, Malahide, Dublin | 2022 |
| 107 | WTS Porterfield | Ireland v Pakistan | Adelaide Oval, Adelaide | 2014/15 |
| 105* | EC Joyce | Ireland v Afghanistan | Civil Service Cricket Club, Stormont, Belfast | 2016 |
| 105 | A Balbirnie | Ireland v Scotland | Harare Sports Club, Harare | 2017/18 |
| 104* | WTS Porterfield | Ireland v Kenya | Ruaraka Sports Club Ground, Nairobi | 2006/07 |
| 104* | WTS Porterfield | Ireland v Canada | SuperSport Park, Centurion | 2008/09 |
| 103 | PR Stirling | Ireland v Pakistan | Castle Avenue, Dublin | 2013 |
| 102 | A Balbirnie | Ireland v United Arab Emirates | ICC Cricket Academy Ground, Dubai | 2017/18 |
| 102 | A Balbirnie | Ireland v South Africa | The Village, Malahide, Dublin | 2021 |
| 101 | WTS Porterfield | Ireland v Scotland | Willowmoore Park Main Oval, Benoni | 2008/09 |
| 101 | PR Stirling | Ireland v Netherlands | Eden Gardens, Kolkata | 2010/11 |
| 101 | PR Stirling | Ireland v Afghanistan | Sharjah Cricket Association Stadium, Sharjah | 2017/18 |
| 101 | A Balbirnie | Ireland v Zimbabwe | Magheramason, Bready | 2019 |
| 101* | HT Tector | Ireland v Zimbabwe | Harare Sports Club, Harare | 2022/23 |
| 100 | WTS Porterfield | Ireland v United Arab Emirates | ICC Cricket Academy Ground, Dubai | 2016/17 |
| 100* | Simranjit Singh | Ireland v South Africa | The Village, Malahide, Dublin | 2021 |
