| 15 Apr 2008 | Other matches in England 2008 | Middlesex Second XI v England Under-19s | Brunton Memorial Ground, Radlett | Won by 5 wkts |
| 16 Apr 2008 | Other matches in England 2008 | Middlesex Second XI v England Under-19s | Brunton Memorial Ground, Radlett | Lost by 5 wkts |
| 18 Apr 2008 | Other matches in England 2008 | Middlesex Second XI v England Under-19s | Brunton Memorial Ground, Radlett | Lost by 149 runs |
| 22 Apr 2008 | Other matches in England 2008 | Berkshire v Middlesex Second XI | Enborne Lodge, Newbury | Abandoned |
| 07 May 2008 | Other matches in England 2008 | Essex and Kent Second XIs v Middlesex Second XI | Garon Park, Southend-on-Sea | Lost by 9 wkts |
| 27 May 2008 | Other matches in England 2008 | Marylebone Cricket Club Young Cricketers v Middlesex Second XI | Brunton Memorial Ground, Radlett | Abandoned |
| 16 Jul 2008 | Other matches in England 2008 | Marylebone Cricket Club Universities v Middlesex Second XI | Brunton Memorial Ground, Radlett | Drawn |
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