| 17 May 2018 | Royal London One-Day Cup 2018 | Middlesex v Essex | Brunton Memorial Ground, Radlett | Lost by 6 wkts |
| 20 May 2018 | Royal London One-Day Cup 2018 | Middlesex v Kent | Brunton Memorial Ground, Radlett | Won by 70 runs |
| 23 May 2018 | Royal London One-Day Cup 2018 | Glamorgan v Middlesex | Sophia Gardens, Cardiff | Won by 2 runs |
| 25 May 2018 | Royal London One-Day Cup 2018 | Sussex v Middlesex | The 1st Central County Ground, Hove | Won by 74 runs |
| 27 May 2018 | Royal London One-Day Cup 2018 | Somerset v Middlesex | The Cooper Associates County Ground, Taunton | Lost by 53 runs |
| 30 May 2018 | Royal London One-Day Cup 2018 | Middlesex v Hampshire | Merchant Taylors' School Ground, Northwood | Lost by 5 wkts |
| 03 Jun 2018 | Royal London One-Day Cup 2018 | Middlesex v Surrey | Lord's Cricket Ground, St John's Wood | Lost by 5 wkts |
| 06 Jun 2018 | Royal London One-Day Cup 2018 | Gloucestershire v Middlesex | Brightside Ground, Bristol | Won by 33 runs |
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