| 216* | BA Godleman | Essex Second XI v Surrey Second XI | The Brit Oval, Kennington | 2010 |
| 210 | AD Brown | Surrey Second XI v Kent Second XI | The Foster's Oval, Kennington | 1992 |
| 203* | F du Plessis | Nottinghamshire Second XI v Minor Counties Under-25s | Brian Wakefield Memorial Ground, Nottingham | 2006 |
| 202* | SC Goldsmith | Derbyshire Second XI v Lancashire Second XI | Four Trees, Checkley | 1992 |
| 196* | SA Marsh | Kent Second XI v Essex Second XI | County Ground, Chelmsford | 2000 |
| 193 | JM Dakin | Leicestershire Second XI v Middlesex Second XI | Grace Road, Leicester | 1996 |
| 193* | DJ Pipe | Worcestershire Second XI v Glamorgan Second XI | The Gnoll, Neath | 2004 |
| 190* | MAH Hammond | Gloucestershire Second XI v Marylebone Cricket Club Young Cricketers | North Parade, Bath | 2015 |
| 188 | P Bainbridge | Durham Second XI v Nottinghamshire Second XI | Bunker Hill, Philadelphia | 1995 |
| 182 | SM Davies | Worcestershire Second XI v Warwickshire Second XI | Old Church Avenue, Harborne | 2006 |
| 180* | DM Ward | Surrey Second XI v Marylebone Cricket Club Young Cricketers | The Foster's Oval, Kennington | 1993 |
| 180* | SW Billings | Kent Second XI v Gloucestershire Second XI | The Kent County Cricket Ground, Beckenham | 2012 |
| 180* | JA Haynes | Worcestershire Second XI v Yorkshire Second XI | Chester Road North, Kidderminster | 2019 |
| 176* | FK Cowdrey | Kent Second XI v Gloucestershire Second XI | Spitfire Ground, St Lawrence, Canterbury | 2015 |
| 173* | JH Barrett | Marylebone Cricket Club Young Cricketers v Leicestershire Second XI | Coventry Road, Lutterworth | 2018 |
| 172 | JC Pooley | Middlesex Second XI v Marylebone Cricket Club Young Cricketers | John Walker's Ground, Southgate | 1994 |
| 172* | AJE Hibbert | Essex Second XI v Sussex Second XI | County Ground, Chelmsford | 1996 |
| 172* | SL Elstone | Derbyshire Second XI v Northamptonshire Second XI | Christchurch Meadows, Belper | 2015 |
| 172 | TC Bruce | Surrey Second XI v Sussex Second XI | London School of Economics Sports Ground, New Malden | 2018 |
| 171 | A Fordham | Northamptonshire Second XI v Yorkshire Second XI | Centre Vale, Todmorden | 1990 |
| 170 | JER Gallian | Lancashire Second XI v Yorkshire Second XI | Park Avenue Cricket Ground, Bradford | 1994 |
| 170* | WPC Weston | Worcestershire Second XI v Hampshire Second XI | Haden Hill Park, Haden Hill | 2002 |
| 170 | JHK Adams | Hampshire Second XI v Glamorgan Second XI | The SWALEC Stadium, Cardiff | 2008 |
| 169* | PD Atkins | Surrey Second XI v Marylebone Cricket Club Young Cricketers | The Foster's Oval, Kennington | 1993 |
| 169 | A Fordham | Northamptonshire Second XI v Leicestershire Second XI | Bedford School Ground, Bedford | 1997 |
| 167* | KA Parsons | Somerset Second XI v Worcestershire Second XI | County Ground, Taunton | 1993 |
| 166 | B Parker | Yorkshire Second XI v Northamptonshire Second XI | Wagon Lane, Bingley | 1991 |
| 163* | N Shahid | Essex Second XI v Marylebone Cricket Club Young Cricketers | Dick Patmore Memorial Ground, Wickford | 1993 |
| 163 | SR Patel | Nottinghamshire Second XI v Essex Second XI | Worksop College Ground, Worksop | 2008 |
| 162 | VS Solanki | Worcestershire Second XI v Somerset Second XI | St Godwalds Park, Bromsgrove | 1997 |
| 162 | TL Maynard | Glamorgan Second XI v Marylebone Cricket Club Young Cricketers | Lower Mill Street, Usk | 2010 |
| 162 | LS Livingstone | Lancashire Second XI v Worcestershire Second XI | Emirates Old Trafford, Manchester | 2015 |
| 161 | JR Wileman | Nottinghamshire Second XI v Lancashire Second XI | Trent Bridge, Nottingham | 1996 |
| 161* | TC Walton | Northamptonshire Second XI v Middlesex Second XI | Campbell Park, Milton Keynes | 1998 |
| 161* | DD Cherry | Glamorgan Second XI v Worcestershire Second XI | Lower Mill Street, Usk | 2002 |
| 160 | MA Thornely | Sussex Second XI v Middlesex Second XI | Uxbridge Cricket Club Ground, Uxbridge | 2009 |
| 159 | JEC Franklin | Nottinghamshire Second XI v Warwickshire Second XI | Edgbaston, Birmingham | 2014 |
| 157 | CS Delport | Leicestershire Second XI v Northamptonshire Second XI | County Ground, Northampton | 2017 |
| 156* | MJ Di Venuto | Durham Second XI v Northamptonshire Second XI | Brandon Lane, Brandon | 2012 |
| 156 | T Banton | Somerset Second XI v Warwickshire Second XI | Scorers, Shirley | 2018 |
| 155 | SC Moore | Worcestershire Second XI v Somerset Second XI | Main Road, Ombersley | 2004 |
| 155 | MA Comber | Essex Second XI v Middlesex Second XI | The Ford County Ground, Chelmsford | 2011 |
| 155 | TJ Moores | Nottinghamshire Second XI v Durham Second XI | Nottinghamshire Sports Ground, Nottingham | 2016 |
| 154 | RJ Bartlett | Somerset Second XI v Gloucestershire Second XI | Combe Park, Bath | 1990 |
| 154* | RSM Morris | Hampshire Second XI v Warwickshire Second XI | Finchampstead Park, Finchampstead | 1993 |
| 154* | WA Dessaur | Nottinghamshire Second XI v Yorkshire Second XI | North Marine Road, Scarborough | 1994 |
| 153* | GFB Scott | Middlesex Second XI v Kent Second XI | Brunton Memorial Ground, Radlett | 2017 |
| 152* | A Lyth | Yorkshire Second XI v Worcestershire Second XI | Chester Road North, Kidderminster | 2009 |
| 152* | SA Northeast | Kent Second XI v Surrey Second XI | St Lawrence Ground, Canterbury | 2010 |
| 152* | AJ Ball | Kent Second XI v Gloucestershire Second XI | The Kent County Cricket Ground, Beckenham | 2017 |
| 151 | NJ Llong | Kent Second XI v Surrey Second XI | St Lawrence Ground, Canterbury | 1992 |
| 151* | CR Taylor | Yorkshire Second XI v Worcestershire Second XI | Chester Road North, Kidderminster | 2009 |
| 151 | AJ Blake | Kent Second XI v Hampshire Second XI | Polo Farm Sports Club, Canterbury | 2015 |
| 151* | KK Jennings | Durham Second XI v Yorkshire Second XI | Emirates Durham International Cricket Ground, Chester-le-Street | 2015 |
| 151 | TP Alsop | Hampshire Second XI v Marylebone Cricket Club Young Cricketers | The Ageas Bowl (Nursery), Southampton | 2016 |
| 150 | N Pratt | Marylebone Cricket Club Young Cricketers v Essex Second XI | Fords Sports Club Ground, Newbury Park | 1992 |
| 150* | AJE Hibbert | Essex Second XI v Kent Second XI | Mote Park, Maidstone | 1996 |
| 150 | T Banton | Somerset Second XI v Middlesex Second XI | Brunton Memorial Ground, Radlett | 2019 |